Metformin inhibits melanoma cell metastasis by suppressing the miR-5100/SPINK5/STAT3 axis
Abstract Melanoma is the most lethal skin cancer characterized by its high metastatic potential. It is urgent to find novel therapy strategies to overcome this feature. Metformin has been confirmed to suppress invasion and migration of various types of cancer. However, additional mechanisms underlyi...
Main Authors: | Dong Suwei, Xiao Yanbin, Wang Jianqiang, Ma Xiang, Peng Zhuohui, Kang Jianping, Wang Yunqing, Li Zhen |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-06-01
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Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | https://doi.org/10.1186/s11658-022-00353-5 |
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