Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil
Abstract Introduction: Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. Objective: To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Nefrologia
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| Series: | Brazilian Journal of Nephrology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002016000300334&lng=en&tlng=en |
| _version_ | 1817992433051369472 |
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| author | Luana Soriano Mota Claudia Maria Costa de Oliveira Francisco Martho Leal Pinheiro Junior Larissa Costa de Oliveira Santos Danilo Gonçalves Nóbrega Paula FBC Fernandes Alda Angélica de Melo Costa Sônia Leite da Silva |
| author_facet | Luana Soriano Mota Claudia Maria Costa de Oliveira Francisco Martho Leal Pinheiro Junior Larissa Costa de Oliveira Santos Danilo Gonçalves Nóbrega Paula FBC Fernandes Alda Angélica de Melo Costa Sônia Leite da Silva |
| author_sort | Luana Soriano Mota |
| collection | DOAJ |
| description | Abstract Introduction: Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. Objective: To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria over a year in a single transplant center. Methods: 255 kidney transplant recipients with deceased donor were included in the study between the years 2011 to 2013 and they were separated into two groups according to the type of donor (expanded criteria donor - ECD - and standard criteria donor - SCD). Results: 231 deceased donor transplants (90.6%) were performed with standard criteria donor (SCD) and 24 (9.4%) with expanded criteria donor (ECD). There was no difference in the prevalence of delayed graft function - DGF - (62.9% vs. 70.8%; p = 0.44). Expanded criteria donor group had lower glomerular filtration rate (GFR) at the end of the 1st year (56.8 ± 26.9 vs. 76.9 ± 23.7; p = 0.001). Patient survival was significantly lower in the ECD group, but the graft survival was not different after death-censored analysis. Conclusion: The ECD group was associated with significantly lower levels of GFR during the first year of transplant and a lower patient survival at the 1st year when compared to the SCD. |
| first_indexed | 2024-04-14T01:26:15Z |
| format | Article |
| id | doaj.art-68ab947bf2804a469a97c3dcfa9eff3e |
| institution | Directory Open Access Journal |
| issn | 2175-8239 |
| language | English |
| last_indexed | 2024-04-14T01:26:15Z |
| publisher | Sociedade Brasileira de Nefrologia |
| record_format | Article |
| series | Brazilian Journal of Nephrology |
| spelling | doaj.art-68ab947bf2804a469a97c3dcfa9eff3e2022-12-22T02:20:25ZengSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology2175-823938333434310.5935/0101-2800.20160051S0101-28002016000300334Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in BrazilLuana Soriano MotaClaudia Maria Costa de OliveiraFrancisco Martho Leal Pinheiro JuniorLarissa Costa de Oliveira SantosDanilo Gonçalves NóbregaPaula FBC FernandesAlda Angélica de Melo CostaSônia Leite da SilvaAbstract Introduction: Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. Objective: To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria over a year in a single transplant center. Methods: 255 kidney transplant recipients with deceased donor were included in the study between the years 2011 to 2013 and they were separated into two groups according to the type of donor (expanded criteria donor - ECD - and standard criteria donor - SCD). Results: 231 deceased donor transplants (90.6%) were performed with standard criteria donor (SCD) and 24 (9.4%) with expanded criteria donor (ECD). There was no difference in the prevalence of delayed graft function - DGF - (62.9% vs. 70.8%; p = 0.44). Expanded criteria donor group had lower glomerular filtration rate (GFR) at the end of the 1st year (56.8 ± 26.9 vs. 76.9 ± 23.7; p = 0.001). Patient survival was significantly lower in the ECD group, but the graft survival was not different after death-censored analysis. Conclusion: The ECD group was associated with significantly lower levels of GFR during the first year of transplant and a lower patient survival at the 1st year when compared to the SCD.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002016000300334&lng=en&tlng=endelayed graft functiongraft ratekidney transplantationsurvival rate. |
| spellingShingle | Luana Soriano Mota Claudia Maria Costa de Oliveira Francisco Martho Leal Pinheiro Junior Larissa Costa de Oliveira Santos Danilo Gonçalves Nóbrega Paula FBC Fernandes Alda Angélica de Melo Costa Sônia Leite da Silva Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil Brazilian Journal of Nephrology delayed graft function graft rate kidney transplantation survival rate. |
| title | Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
| title_full | Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
| title_fullStr | Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
| title_full_unstemmed | Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
| title_short | Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
| title_sort | comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in brazil |
| topic | delayed graft function graft rate kidney transplantation survival rate. |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002016000300334&lng=en&tlng=en |
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