Effect of pre-infusion of hypertonic saline on postoperative delirium in geriatric patients undergoing shoulder arthroscopy: a randomized controlled trial

Effect of pre-infusion of hypertonic saline on postoperative delirium in geriatric patients undergoing shoulder arthroscopy: a randomized controlled trial

Abstract Background Neuroinflammation may be a potential mechanism of postoperative delirium (POD) in geriatric patients, and hypertonic saline (HS) has immunomodulatory properties. The purpose of this study was to investigate whether HS could reduce the incidence of POD in elderly patients and its...

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Bibliographic Details
Main Authors: Fang Xu, Yanan Li, Xupeng Wang, Ran Sun, Zilei Zheng, Qi Zhang, Mingyang Gao, Wei Tao, Juan Zhao, Qiujun Wang
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Anesthesiology
Subjects:
Postoperative delirium
Neuroinflammation
Hypertonic saline
Neutrophils
Cytokines
Online Access:https://doi.org/10.1186/s12871-023-02340-5

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