Phage display engineered T cell receptors as tools for the study of tumor peptide-MHC interactions

Phage display engineered T cell receptors as tools for the study of tumor peptide-MHC interactions

Cancer immunotherapy has finally come of age, demonstrated by recent progress in strategies that engage the endogenous adaptive immune response in tumor killing. Occasionally, significant and durable tumor regression has been achieved. A giant leap forward was the demonstration that the pre-existing...

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Bibliographic Details
Main Authors: Geir Åge Løset, Gøril eBerntzen, Terje eFrigstad, Sylvie ePollmann, Kristin Støen Gunnarsen, Inger eSandlie
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Oncology
Subjects:
Antigen Presentation
T cell receptor
MHC
phage display
tumor immunity
immunotherapy of cancer
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00378/full

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