Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicin
Single cell transcriptomics pinpoints a cell subpopulation that could be involved in inducing cellular senescence of the retinal pigment epithelium, which in turn may construe retinal degenerative disease.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03676-3 |
| _version_ | 1811287118898528256 |
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| author | Hyungwoo Lee Ho-Yeon Lee Jae-Byoung Chae Chul-Woo Park Chaekyu Kim Ja-Hyoung Ryu Jiwon Jang Namshin Kim Hyewon Chung |
| author_facet | Hyungwoo Lee Ho-Yeon Lee Jae-Byoung Chae Chul-Woo Park Chaekyu Kim Ja-Hyoung Ryu Jiwon Jang Namshin Kim Hyewon Chung |
| author_sort | Hyungwoo Lee |
| collection | DOAJ |
| description | Single cell transcriptomics pinpoints a cell subpopulation that could be involved in inducing cellular senescence of the retinal pigment epithelium, which in turn may construe retinal degenerative disease. |
| first_indexed | 2024-04-13T03:13:14Z |
| format | Article |
| id | doaj.art-68b1c7dc4a644fb1a42fc774bda268d3 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-13T03:13:14Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-68b1c7dc4a644fb1a42fc774bda268d32022-12-22T03:04:59ZengNature PortfolioCommunications Biology2399-36422022-07-015111110.1038/s42003-022-03676-3Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicinHyungwoo Lee0Ho-Yeon Lee1Jae-Byoung Chae2Chul-Woo Park3Chaekyu Kim4Ja-Hyoung Ryu5Jiwon Jang6Namshin Kim7Hyewon Chung8Department of Ophthalmology, Konkuk University School of MedicineGenome Editing Research Center, Korea Research Institute of Bioscience and BiotechnologyDepartment of Ophthalmology, Konkuk University School of MedicineDepartment of Ophthalmology, Konkuk University School of MedicineFusion Biotechnology, Inc.Department of Chemistry, Ulsan National Institute of Science and TechnologyDepartment of Life Sciences, Pohang University of Science and Technology (POSTECH)Genome Editing Research Center, Korea Research Institute of Bioscience and BiotechnologyDepartment of Ophthalmology, Konkuk University School of MedicineSingle cell transcriptomics pinpoints a cell subpopulation that could be involved in inducing cellular senescence of the retinal pigment epithelium, which in turn may construe retinal degenerative disease.https://doi.org/10.1038/s42003-022-03676-3 |
| spellingShingle | Hyungwoo Lee Ho-Yeon Lee Jae-Byoung Chae Chul-Woo Park Chaekyu Kim Ja-Hyoung Ryu Jiwon Jang Namshin Kim Hyewon Chung Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicin Communications Biology |
| title | Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicin |
| title_full | Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicin |
| title_fullStr | Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicin |
| title_full_unstemmed | Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicin |
| title_short | Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicin |
| title_sort | single cell transcriptome of the mouse retinal pigment epithelium in response to a low dose of doxorubicin |
| url | https://doi.org/10.1038/s42003-022-03676-3 |
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