Enhancing the efficacy of Hypericum perforatum in the treatment of an experimental model of multiple sclerosis using gold nanoparticles: an in vivo study

Enhancing the efficacy of Hypericum perforatum in the treatment of an experimental model of multiple sclerosis using gold nanoparticles: an in vivo study

Objective: Hypericum perforatum is a herbal medicine used in traditional medicine for the treatment of depression due to its antidepressant and anti-inflammatory activities. Therefore, we evaluated the therapeutic efficacy of H. perforatum extract (HPE) in combination with gold nanoparticles (HPE-GN...

Full description

Bibliographic Details
Main Authors:	Mahmoud Mahmoudi, Maryam Rastin, Mohammad Kazemi Arababadi, Akbar Anaeigoudari, Reza Nosratabadi
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2022-05-01
Series:	Avicenna Journal of Phytomedicine
Subjects:	hypericum perforatum l multiple sclerosis experimental autoimmune encephalomyelitis gold nanoparticle myelin oligodendrocyte glycoprotein
Online Access:	https://ajp.mums.ac.ir/article_19574_d8ef1a0c3ada92f1ac801aedf2a989c2.pdf

Similar Items

Berberine promotes immunological outcomes and decreases neuroinflammation in the experimental model of multiple sclerosis through the expansion of Treg and Th2 cells
by: Maryam J. Tavaf, et al.
Published: (2023-01-01)

Antidermatophyte Activity of the Essential oil of Hypericum perforatum of North of Iran
by: M Larypoor, et al.
Published: (2009-09-01)

Oral Administration of Myelin Oligodendrocyte Glycoprotein Attenuates Experimental Autoimmune Encephalomyelitis through Induction of Th2/Treg Cells and Suppression of Th1/Th17 Immune Responses
by: Dariush Haghmorad, et al.
Published: (2022-11-01)

Alterations of peripheral nerve excitability in an experimental autoimmune encephalomyelitis mouse model for multiple sclerosis
by: Nathalia Bernardes Teixeira, et al.
Published: (2020-09-01)

Effect of hypericum perforatum cream on perineal wound healing in primiparous women
by: Somayeh Yahya, et al.
Published: (2020-08-01)

Effect of Hypericum perforatum L. for treatment of premenstrual syndrome
by: M Pakgohar, et al.
Published: (2005-09-01)

Response Surface Methodology Approach to Optimize the Expression of Thioredoxin-MOG Fusion Protein
by: Maryam Radmard, et al.
Published: (2024-04-01)

Aspectos botânicos, químicos, farmacológicos e terapêuticos do Hypericum perforatum L.
by: A.C.S. Alves, et al.
Published: (2014-09-01)

Usage of Hypericum perforatum Microcapsules in the Production of Ayran (Drinking Yoghurt)
by: Fadime Seyrekoğlu, et al.
Published: (2021-12-01)

Generation of a murine model of chronic progressive Experimental Autoimmune Encephalomyelitis for molecular pharmacology studies in Multiple Sclerosis
by: Karelia Macías-Cosme, et al.

Cadmium, Mercury and Lead in Hypericum perforatum L. collected in Western Serbia
by: Đurović D., et al.
Published: (2013-04-01)

Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome
by: M Pakgohar, et al.
Published: (2004-07-01)

Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome
by: Pakgohar M, et al.
Published: (2004-03-01)

Neuroprotective activity of Hypericum perforatum and its major components
by: Ana Isabel Oliveira, et al.
Published: (2016-07-01)

The effects of hydro- alcoholic extract of Hypericum perforatum on cell migration and inflammatory mediators production in acute peritonitis induced by Zymosan in NMRI mice
by: SH Ghasemi, et al.
Published: (2017-02-01)

Immunomudulatory effects of hydroalcoholic extract of Hypericum perforatum
by: Seyyed Meysam Abtahi Froushani, et al.
Published: (2014-12-01)

Assessment of Genetic Diversity in the Populations of Hypericum perforatum L. Using AFLP Markers
by: L Rezaei, et al.
Published: (2012-11-01)

An in vivo study of Hypericum perforatum in a niosomal topical drug delivery system
by: Mohamed Ali, et al.
Published: (2018-01-01)

Development of methods for express-evaluation of resources of Hypericum perforatum L.
by: V. M. Minarchenko
Published: (2013-12-01)

Targeted Expression of Myelin Autoantigen in the Periphery Induces Antigen-Specific T and B Cell Tolerance and Ameliorates Autoimmune Disease
by: Shin-Young Na, et al.
Published: (2021-06-01)

Impact of histone modifier-induced protection against autoimmune encephalomyelitis on multiple sclerosis treatment
by: Sundararajan Jayaraman, et al.
Published: (2022-10-01)

ANTI-INFLAMMATORY, ANALGESIC ACTIVITY, ACUTE TOXICITY AND HYPERICINS CONTENT OF IRANIAN HYPERICUM PERFORATUM
by: M M. Mahmoudi,, et al.
Published: (2006-08-01)

Comparison of Systemic and Topical Hypericum Perforatum on Diabetic Surgical Wounds
by: Mehmet Altıparmak, et al.
Published: (2018-01-01)

Greenhouse test for the resistance to root and stem rot of Hypericum perforatum L. accessions
by: A. Kačergius, et al.
Published: (2002-12-01)

Antiproliferative effects of Tanaceti partheni, Hypericum perforatum and propolis on HeLa cells
by: Cenić-Milošević Desanka, et al.
Published: (2014-01-01)

A Spontaneous Model of Experimental Autoimmune Encephalomyelitis Provides Evidence of MOG-Specific B Cell Recruitment and Clonal Expansion
by: Florent Salvador, et al.
Published: (2022-02-01)

Chitosan Gel Containing Hypericum perforatum Extract Inhibiting Effect on Oxidative Stress in Burn Wounds of Rats
by: Pouria Khanzadeh, et al.
Published: (2024-04-01)

Anfälligkeit von Johanniskraut (Hypericum perforatum) gegenüber dem Welkeerreger Colletotrichum gloeosporioides - Gesamtauswertung mehrerer Resistenzprüfungen-
by: Wahl, Susanne, et al.
Published: (2018-09-01)

Recognition of a high affinity MHC class I-restricted epitope of myelin oligodendrocyte glycoprotein by CD8+ T cells derived from autoantigen-deficient mice.
by: Melanie D Leech, et al.
Published: (2011-05-01)

Direct modulation of myelin-autoreactive CD4+ and CD8+ T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, CD47 and multiple regulatory molecules
by: Pei W, et al.
Published: (2018-06-01)

Grzyby zagrażające uprawie dziurawca zwyczajnego (Hypericum perforatum L.) w województwie lubelskim
by: Beata Zimowska, et al.
Published: (2004-06-01)

Variation in quantitative yield and hypericin content of St. John’s wort., Hypericum perforatum L.
by: H Naghdi Badi, et al.
Published: (2004-09-01)

Essential oil composition and variability of Hypericum perforatum L. from wild population in Kosovo
by: Hajdari Avni, et al.
Published: (2014-06-01)

Aplicações terapêuticas do Hypericum perforatum (erva-de-são-joão) no tratamento da ansiedade e depressão
by: Alany Lima Soares Chagas, et al.
Published: (2023-06-01)

Micro-nano particulate compositions of Hypericum perforatum L in ultra high diluted succussed solution medicinal products
by: Dimitris Kalliantas, et al.
Published: (2021-04-01)

Mechanisms Governing Oligodendrocyte Viability in Multiple Sclerosis and Its Animal Models
by: Zhixin Lei, et al.
Published: (2024-01-01)

Development of controlled delivery systems by nanoliposomes of Hypericum perforatum L. extracts
by: Özlem Erdal Altıntaş, et al.
Published: (2023-03-01)

Optimization of HPLC method for the isolation of Hypericum perforatum L. methanol extract
by: Stamenković, J., et al.
Published: (2013-12-01)

Effects of Hypericum perforatum extract on IgG titer, leukocytes subset and spleen index in rats
by: Tahereh Aghili, et al.
Published: (2014-11-01)

Comparison of the Effects of Hypericum perforatum extract and its Microemulsion with Aloe vera Extract on Brucella melitensis
by: Mahsa Tabibnejad, et al.
Published: (2018-03-01)