Prevalence of Opioid Use Disorder among Patients with Cancer-Related Pain: A Systematic Review
Background: The opioid use disorder is an international public health problem. Over the past 20 years it has been the subject of numerous publications concerning patients treated for chronic pain other than cancer-related. Patients with cancer-related pain are also at risk of opioid use disorder. Th...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/6/1594 |
| _version_ | 1797470533461213184 |
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| author | Céline Preux Marion Bertin Andréa Tarot Nicolas Authier Nathalie Pinol David Brugnon Bruno Pereira Virginie Guastella |
| author_facet | Céline Preux Marion Bertin Andréa Tarot Nicolas Authier Nathalie Pinol David Brugnon Bruno Pereira Virginie Guastella |
| author_sort | Céline Preux |
| collection | DOAJ |
| description | Background: The opioid use disorder is an international public health problem. Over the past 20 years it has been the subject of numerous publications concerning patients treated for chronic pain other than cancer-related. Patients with cancer-related pain are also at risk of opioid use disorder. The primary objective of this literature review was to determine the prevalence of opioid use disorder in patients with cancer-related chronic pain. Its secondary objective was to identify the characteristics of these opioid users. Methods: This is a literature review of studies published over the last twenty years, from 1 January 2000 to 31 December 2020 identified by searching the three main medical databases: Pubmed, Cochrane, and Embase. A meta-analysis took account of between and within-study variability with the use of random-effects models estimated by the DerSimonian and Laird method. Results: The prevalence of opioid use disorder was 8% (1–20%) and of the risk of use disorder was 23.5% (19.5–27.8%) with <i>I</i><sup>2</sup> values of 97.8% and 88.7%, respectively. Conclusions: Further studies are now needed on the prevalence of opioid use disorder in patients treated for cancer-related chronic pain. A screening scale adapted to this patient population is urgently needed. |
| first_indexed | 2024-03-09T19:37:32Z |
| format | Article |
| id | doaj.art-68b7e1de9c874dbda44f4b8b16c47e89 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T19:37:32Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-68b7e1de9c874dbda44f4b8b16c47e892023-11-24T01:48:59ZengMDPI AGJournal of Clinical Medicine2077-03832022-03-01116159410.3390/jcm11061594Prevalence of Opioid Use Disorder among Patients with Cancer-Related Pain: A Systematic ReviewCéline Preux0Marion Bertin1Andréa Tarot2Nicolas Authier3Nathalie Pinol4David Brugnon5Bruno Pereira6Virginie Guastella7Palliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, FrancePalliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, FrancePalliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, FranceNeuro-Dol, Service Pharmacologie Médicale, Centres d’Addictovigilance et Pharmacovigilance, Centre Evaluation et Traitement de la Douleur, Inserm, CHU Clermont-Ferrand, Université de Clermont Auvergne, F-63001 Clermont-Ferrand, FranceCentre de Documentation et Recherche de la Faculté de Médecine, CHU Clermont-Ferrand, Université de Clermont Auvergne, F-63000 Clermont-Ferrand, FrancePalliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, FranceUnité de Biostatistiques, Direction de la Recherche Clinique et de l’Innovation, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, FrancePalliative Care Center, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, FranceBackground: The opioid use disorder is an international public health problem. Over the past 20 years it has been the subject of numerous publications concerning patients treated for chronic pain other than cancer-related. Patients with cancer-related pain are also at risk of opioid use disorder. The primary objective of this literature review was to determine the prevalence of opioid use disorder in patients with cancer-related chronic pain. Its secondary objective was to identify the characteristics of these opioid users. Methods: This is a literature review of studies published over the last twenty years, from 1 January 2000 to 31 December 2020 identified by searching the three main medical databases: Pubmed, Cochrane, and Embase. A meta-analysis took account of between and within-study variability with the use of random-effects models estimated by the DerSimonian and Laird method. Results: The prevalence of opioid use disorder was 8% (1–20%) and of the risk of use disorder was 23.5% (19.5–27.8%) with <i>I</i><sup>2</sup> values of 97.8% and 88.7%, respectively. Conclusions: Further studies are now needed on the prevalence of opioid use disorder in patients treated for cancer-related chronic pain. A screening scale adapted to this patient population is urgently needed.https://www.mdpi.com/2077-0383/11/6/1594meta-analysissystematic reviewprevalenceopioid use disordercancerchronic pain |
| spellingShingle | Céline Preux Marion Bertin Andréa Tarot Nicolas Authier Nathalie Pinol David Brugnon Bruno Pereira Virginie Guastella Prevalence of Opioid Use Disorder among Patients with Cancer-Related Pain: A Systematic Review Journal of Clinical Medicine meta-analysis systematic review prevalence opioid use disorder cancer chronic pain |
| title | Prevalence of Opioid Use Disorder among Patients with Cancer-Related Pain: A Systematic Review |
| title_full | Prevalence of Opioid Use Disorder among Patients with Cancer-Related Pain: A Systematic Review |
| title_fullStr | Prevalence of Opioid Use Disorder among Patients with Cancer-Related Pain: A Systematic Review |
| title_full_unstemmed | Prevalence of Opioid Use Disorder among Patients with Cancer-Related Pain: A Systematic Review |
| title_short | Prevalence of Opioid Use Disorder among Patients with Cancer-Related Pain: A Systematic Review |
| title_sort | prevalence of opioid use disorder among patients with cancer related pain a systematic review |
| topic | meta-analysis systematic review prevalence opioid use disorder cancer chronic pain |
| url | https://www.mdpi.com/2077-0383/11/6/1594 |
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