HIF-1α Dependent Upregulation of ZIP8, ZIP14, and TRPA1 Modify Intracellular Zn<sup>2+</sup> Accumulation in Inflammatory Synoviocytes

HIF-1α Dependent Upregulation of ZIP8, ZIP14, and TRPA1 Modify Intracellular Zn<sup>2+</sup> Accumulation in Inflammatory Synoviocytes

Intracellular free zinc ([Zn<sup>2+</sup>]<sub>i</sub>) is mobilized in neuronal and non-neuronal cells under physiological and/or pathophysiological conditions; therefore, [Zn<sup>2+</sup>]<sub>i</sub> is a component of cellular signal transduction in...

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Bibliographic Details
Main Authors: Noriyuki Hatano, Masaki Matsubara, Hiroka Suzuki, Yukiko Muraki, Katsuhiko Muraki
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
TRPA1
ZIP8
ZIP14
intracellular Zn<sup>2+</sup> concentration
synoviocytes
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/12/6349

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