Anti-cholesterol triterpenoid acids from Saurauia vulcani Korth. (Actinidiaceae)
Two triterpenoid compounds, 3β-hydroxy-Olean-12-en- 28-oic acid (1) and 3,19-Dihydroxyurs-12-en-28-oic acid (2) were isolated from the leaves of Saurauia vulcani Korth. (Actinidiaceae). The chemical structures of compounds 1–2 were elucidated with spectroscopic data (UV, IR, 1H, 13C, DEPT 135º, HMQC...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-01-01
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| Series: | International Journal of Food Properties |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10942912.2019.1650762 |
| Summary: | Two triterpenoid compounds, 3β-hydroxy-Olean-12-en- 28-oic acid (1) and 3,19-Dihydroxyurs-12-en-28-oic acid (2) were isolated from the leaves of Saurauia vulcani Korth. (Actinidiaceae). The chemical structures of compounds 1–2 were elucidated with spectroscopic data (UV, IR, 1H, 13C, DEPT 135º, HMQC, HMBC, 1H-1H COSY NMR) and MS as well as compared with previously reported spectra data. All the compounds were evaluated for their anti-cholesterol activity by the Liebermann-Burchard (LB) colorimetric assay. Compound 1–2 showed a remarkable anti-cholesterol activity. Most importantly, the raised concentration of 1–2 exhibited a dose-dependent manner. The discoveries of anti-cholesterol compounds 1–2 were first reported. |
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| ISSN: | 1094-2912 1532-2386 |