Enantioselective access to tricyclic tetrahydropyran derivatives by a remote hydrogen bonding mediated intramolecular IEDHDA reaction
Although the hetero-Diels–Alder reaction is a staple of organic chemistry, catalytic asymmetric versions of the inverse-electron demand variant often require specially engineered substrates for the reaction to work. Here the authors cyclize non-activated alkenes with α,β-unsaturated ketones or aldeh...
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Bibliographic Details
| Main Authors: |
Min Jin,
Congyun Tang,
Yingying Li,
Shuai Yang,
Ying-Tao Yang,
Lin Peng,
Xiao-Nian Li,
Wenjing Zhang,
Zhili Zuo,
Fabien Gagosz,
Liang-Liang Wang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-12-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-27521-z
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