A large-scale organoid-based screening platform to advance drug repurposing in pancreatic cancer
Hirt et al.1 report an automated, high-throughput drug screening platform for organoid cultures to enable repurposing of previously approved drugs for pancreatic cancers harboring specific genetic alterations. The pancreatic cancer organoid biobank also represents a valuable tool to uncover new drug...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-02-01
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Series: | Cell Genomics |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666979X22000179 |
Summary: | Hirt et al.1 report an automated, high-throughput drug screening platform for organoid cultures to enable repurposing of previously approved drugs for pancreatic cancers harboring specific genetic alterations. The pancreatic cancer organoid biobank also represents a valuable tool to uncover new drug-gene interactions in pancreatic tumors. |
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ISSN: | 2666-979X |