Pharmacological treatment of tics in Gilles de la Tourette Syndrome
Tourette syndrome is a neurodevelopmental disorder characterised by the chronic presence of multiple motor tics (e.g. eye blinking, shoulder shrugging, etc.) and at least one vocal/phonic tic (e.g. grunting or sniffing). The clinical picture of patients with Tourette syndrome is often complicated by...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SEEd
2011-12-01
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| Series: | Clinical Management Issues |
| Subjects: | |
| Online Access: | https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/496 |
| _version_ | 1818577630339792896 |
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| author | Andrea E. Cavanna Andrea Nani |
| author_facet | Andrea E. Cavanna Andrea Nani |
| author_sort | Andrea E. Cavanna |
| collection | DOAJ |
| description | Tourette syndrome is a neurodevelopmental disorder characterised by the chronic presence of multiple motor tics (e.g. eye blinking, shoulder shrugging, etc.) and at least one vocal/phonic tic (e.g. grunting or sniffing). The clinical picture of patients with Tourette syndrome is often complicated by tic-related behavioural problems and associated psychopathology. The pathophysiology of Tourette syndrome is poorly understood, however converging evidence from neuroimaging studies suggests abnormalities within the fronto-striatal pathways. The pharmacological management of the tic symptoms focuses on the dopaminergic and noradrenergic pathways and aims to improve the health-related quality of life of patients. |
| first_indexed | 2024-12-16T06:32:58Z |
| format | Article |
| id | doaj.art-68bcfa3d0c7c45f29bc594703a9d9867 |
| institution | Directory Open Access Journal |
| issn | 1973-4832 2283-3137 |
| language | English |
| last_indexed | 2024-12-16T06:32:58Z |
| publishDate | 2011-12-01 |
| publisher | SEEd |
| record_format | Article |
| series | Clinical Management Issues |
| spelling | doaj.art-68bcfa3d0c7c45f29bc594703a9d98672022-12-21T22:40:50ZengSEEdClinical Management Issues1973-48322283-31372011-12-015414515510.7175/cmi.v5i4.496458Pharmacological treatment of tics in Gilles de la Tourette SyndromeAndrea E. Cavanna0Andrea Nani1Michael Trimble Neuropsychiatry Research Group, University of Birmingham and BSMHFT, Birmingham, UK. Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology and University College London, UKMichael Trimble Neuropsychiatry Research Group, University of Birmingham and BSMHFT, Birmingham, UKTourette syndrome is a neurodevelopmental disorder characterised by the chronic presence of multiple motor tics (e.g. eye blinking, shoulder shrugging, etc.) and at least one vocal/phonic tic (e.g. grunting or sniffing). The clinical picture of patients with Tourette syndrome is often complicated by tic-related behavioural problems and associated psychopathology. The pathophysiology of Tourette syndrome is poorly understood, however converging evidence from neuroimaging studies suggests abnormalities within the fronto-striatal pathways. The pharmacological management of the tic symptoms focuses on the dopaminergic and noradrenergic pathways and aims to improve the health-related quality of life of patients.https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/496PsychopathologyPharmacological treatmentTourette SyndromeTics |
| spellingShingle | Andrea E. Cavanna Andrea Nani Pharmacological treatment of tics in Gilles de la Tourette Syndrome Clinical Management Issues Psychopathology Pharmacological treatment Tourette Syndrome Tics |
| title | Pharmacological treatment of tics in Gilles de la Tourette Syndrome |
| title_full | Pharmacological treatment of tics in Gilles de la Tourette Syndrome |
| title_fullStr | Pharmacological treatment of tics in Gilles de la Tourette Syndrome |
| title_full_unstemmed | Pharmacological treatment of tics in Gilles de la Tourette Syndrome |
| title_short | Pharmacological treatment of tics in Gilles de la Tourette Syndrome |
| title_sort | pharmacological treatment of tics in gilles de la tourette syndrome |
| topic | Psychopathology Pharmacological treatment Tourette Syndrome Tics |
| url | https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/496 |
| work_keys_str_mv | AT andreaecavanna pharmacologicaltreatmentofticsingillesdelatourettesyndrome AT andreanani pharmacologicaltreatmentofticsingillesdelatourettesyndrome |