3-Methyl-1-phenyl-1H-pyrazol-5-yl 2-Bromo-3-furan-carboxylate

3-Methyl-1-phenyl-1H-pyrazol-5-yl 2-Bromo-3-furan-carboxylate

The reaction of 3-methyl-1-phenyl-2-pyrazolin-5-one and 2-bromo-3-furoyl chloride in the presence of Ca(OH)2 in 1,4-dioxane gave the title compound. The latter was also obtained in much higher yield upon reaction of the starting materials in the system dichloromethane / triethylamine. Detailed spect...

Full description

Bibliographic Details
Main Authors:	Karin Schalle, Changbin Guo, Wolfgang Holzer
Format:	Article
Language:	English
Published:	MDPI AG 2009-07-01
Series:	Molbank
Subjects:	pyrazolones aroylation NMR spectroscopy
Online Access:	http://www.mdpi.com/1422-8599/2009/3/M603/

Similar Items

5-Methyl-4-(3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
by: Ismail Ghandour, et al.
Published: (2017-06-01)

5-Methyl-4-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-phenyl-1H-pyrazol-3(2H)-one
by: Gregory L. Powell, et al.
Published: (2020-02-01)

A Convenient Approach to Heterocyclic Building Blocks: Synthesis of Novel Ring Systems Containing a [5,6]Pyrano[2,3-c]pyrazol-4(1H)-one Moiety
by: Wolfgang Holzer, et al.
Published: (2007-01-01)

Crystal structure of 4-[(2,4-dichlorophenyl)(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-5-methyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
by: Balbir Kumar, et al.
Published: (2015-10-01)

Co-crystallization of a neutral molecule and its zwitterionic tautomer: structure and Hirshfeld surface analysis of 5-methyl-4-(5-methyl-1H-pyrazol-3-yl)-2-phenyl-2,3-dihydro-1H-pyrazol-3-one 5-methyl-4-(5-methyl-1H-pyrazol-2-ium-3-yl)-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-1-ide monohydrate
by: Abdullah M. Asiri, et al.
Published: (2019-05-01)

4-[5-(3,5-Difluorophenyl)furan-2-yl]-2,3,7-triazaspiro[4.5]dec-3-en-1-one Hydrochloride
by: Balladka Kunhanna Sarojini, et al.
Published: (2012-08-01)

4,4’-[(2-Chlorophenyl)methylene]bis[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-5-ol]
by: Wolfgang Holzer, et al.
Published: (2009-07-01)

(4Z)-4-[1-(2-Aminoanilino)ethylidene]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one
by: Mohamed Samba, et al.
Published: (2017-02-01)

Organocatalytic Regio- and Enantioselective (3+3)-Annulation of 2-(4H-Benzo[d][1,3]oxazin-4-yl)acrylates with 2,4-Dihydro-3H-pyrazol-3-ones
by: Zhongyue Lu, et al.
Published: (2023-12-01)

Crystal structure of 4-(benzo[d]thiazol-2-yl)-1,2-dimethyl-1H-pyrazol-3(2H)-one
by: Heba A. Elboshi, et al.
Published: (2024-03-01)

X-Ray Supramolecular Structure, NMR Spectroscopy and Synthesis of 3-Methyl-1-phenyl-1H-chromeno[4,3-c]pyrazol-4-ones Formed by the Unexpected Cyclization of 3-[1-(Phenyl-hydrazono)ethyl]-chromen-2-ones
by: Efren V. García-Baez, et al.
Published: (2011-01-01)

4-Bromo-3-methoxy-1-phenyl-1H-pyrazole
by: Algirdas Šačkus, et al.
Published: (2009-11-01)

Synthesis, and Anticancer Evaluation of 4-[(Indol-3-yl)-arylmethyl]-1-phenyl-3-methyl-5-pyrazolone Derivatives via a Magnetic Aminated Starch Biocatalyst
by: Ali Ramshini, et al.
Published: (2023-05-01)

Synthesis of new trifluoromethyl-containing 1-(3,5-dialkyl-4-hydroxybenzyl)-pyrazole and -pyrazol-5-one deriatives and their corresponding aroxyls
by: Dinoiu Vasile, et al.
Published: (2006-01-01)

Regioselective Synthesis of 5- and 3-Hydroxy-<i>N</i>-Aryl-1<i>H</i>-Pyrazole-4-Carboxylates and Their Evaluation as Inhibitors of <i>Plasmodium falciparum</i> Dihydroorotate Dehydrogenase
by: Luka Vah, et al.
Published: (2022-07-01)

Crystal structure of 4-{(E)-[2-(pyridin-4-ylcarbonyl)hydrazin-1-ylidene]methyl}phenyl acetate monohydrate
by: Riya Datta, et al.
Published: (2015-02-01)

3-(4-Fluorophenyl)-<em>N</em>-[4-(4-furan-2-yl-1-oxo-2,3,7-triazaspiro[4.5]dec-3-en-2-yl)phenyl]propionamide Hydrochloride
by: Badiadka Narayana, et al.
Published: (2012-08-01)

N,N’-Bis-(2,5-dimethyl-3-oxo-1-phenyl-2,3-dihydro-1H-pyrazol-4-yl)phthalamide
by: Erdoğan Dağci, et al.
Published: (2012-04-01)

Design, synthesis, antimicrobial evaluations and in silico studies of novel pyrazol-5(4H)-one and 1H-pyrazol-5-ol derivatives
by: Em Canh Pham, et al.
Published: (2022-03-01)

<em>N</em>-(3,4-Dimethoxyphenyl)-4-oxo-2,3,7-triazaspiro[4.5]dec-1-ene-1-carboxamide Hydrochloride
by: Seranthimata Samshuddin, et al.
Published: (2012-08-01)

Synthesis, characterization and in vitro antimicrobial activity of novel fused pyrazolo[3,4-c]pyridazine, pyrazolo[3,4-d]pyrimidine, thieno[3,2-c]pyrazole and pyrazolo[3′,4′:4,5]thieno[2,3-d]pyrimidine derivatives
by: Mohamed A. M. Abdel Reheim, et al.
Published: (2017-11-01)

5-Chloro-4-iodo-1,3-dimethyl-1H-pyrazole
by: Gytė Vilkauskaitė, et al.
Published: (2009-09-01)

Crystal structure of aqua[(E)-N′-(5-bromo-2-oxidobenzylidene-κO)benzohydrazidato-κ2O,N′]dioxidomolybdenum(VI) dimethylformamide monosolvate
by: Radhika Sudheer, et al.
Published: (2015-06-01)

Sodium dodecyl benzene sulfonate-catalyzed reaction for aromatic aldehydes with 1-phenyl-3-methyl-5-pyrazolone in aqueous media
by: Yongjun Zheng, et al.
Published: (2018-07-01)

Synthesis and Crystal Structures of 4,5-Dihydroimidazo[1,5-b]pyrazol-6-ones
by: Antonio Guirado, et al.
Published: (2020-10-01)

Synthesis and anti-depressant evaluation of novel pyrazolone derivatives
by: Vijay Kumar Merugumolu, et al.
Published: (2016-05-01)

In vitro antimicrobial evaluation of pyrazolone derivatives
by: Leile Rahimi Ahar, et al.
Published: (2015-02-01)

Electrochemical/I– Dual-Catalyzed Access to Sulfonated Pyrazoles under External Oxidant-Free Conditions
by: Jing Ma, et al.
Published: (2023-06-01)

Convenient Synthesis of Benziodazolone: New Reagents for Direct Esterification of Alcohols and Amidation of Amines
by: Michael T. Shea, et al.
Published: (2021-12-01)

Synthesis, Crystal Structure, and Supramolecular Understanding of 1,3,5-Tris(1-phenyl-1H-pyrazol-5-yl)benzenes
by: Marcos A. P. Martins, et al.
Published: (2017-12-01)

Exploring 2-Tetradecanoylimino-3-aryl-4-methyl-1,3-thiazolines Derivatives as Alkaline Phosphatase Inhibitors: Biochemical Evaluation and Computational Analysis
by: Aftab Ahmed, et al.
Published: (2022-10-01)

(Furan-2-yl)(5-hydroxy-3-methyl-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)methanone
by: Hadi Kargar, et al.
Published: (2011-02-01)

Behaviour of Some Activated Nitriles Toward Barbituric Acid, Thiobarbituric Acid and 3-Methyl-1-Phenylpyrazol-5-one
by: M. M. Habashy, et al.
Published: (2000-05-01)

4-[(3,5-Dimethyl-1<i>H</i>-pyrazol-1-yl)methyl]-4-methyl-2-phenyl-4,5-dihydrooxazole
by: Sara Hajib, et al.
Published: (2019-07-01)

Synthesis of some pyrazolone derivatives from ciprofloxacin and study of their cytotoxicity
by: Hari Pado Devnath, et al.
Published: (2010-06-01)

Novel PD-L1-Targeted Phenyl-Pyrazolone Derivatives with Antioxidant Properties
by: Romain Regnault, et al.
Published: (2023-04-01)

Electrochemical Behavior and Voltammetric Determination of Two Synthetic Aroyl Amides Opioids
by: Andrea Capucciati, et al.
Published: (2023-03-01)

Spectroscopic and ab-initio study of schiff base ligand 4-[(2-hydroxyethylamino)-methylene]-5-methyl-2-p-tolyl-2,4-dihydro-pyrazol-3-one
by: Kiran R. Surati, et al.
Published: (2006-12-01)

4-[5-(Furan-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide
by: Abdullah M. Asiri, et al.
Published: (2012-04-01)

Synthesis of 5-Substituted 3-Amino-1H-Pyrazole-4-Carbonitriles as Precursors for Microwave Assisted Regiospecific Syntheses of Pyrazolo[1,5-a]Pyrimidines
by: Fawzia Al-Qalaf, et al.
Published: (2008-12-01)