PDGF, NT-3 and IGF-2 in combination induced transdifferentiation of muscle-derived stem cells into Schwann cell-like cells.

PDGF, NT-3 and IGF-2 in combination induced transdifferentiation of muscle-derived stem cells into Schwann cell-like cells.

Muscle-derived stem cells (MDSCs) are multipotent stem cells with a remarkable long-term self-renewal and regeneration capacity. Here, we show that postnatal MDSCs could be transdifferentiated into Schwann cell-like cells upon the combined treatment of three neurotrophic factors (PDGF, NT-3 and IGF-...

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Bibliographic Details
Main Authors: Yi Tang, Hua He, Ning Cheng, Yanling Song, Weijin Ding, Yingfan Zhang, Wenhao Zhang, Jie Zhang, Heng Peng, Hua Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3891637?pdf=render

Internet

http://europepmc.org/articles/PMC3891637?pdf=render

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