Wilforine inhibits rheumatoid arthritis pathology through the Wnt11/β-catenin signaling pathway axis

Wilforine inhibits rheumatoid arthritis pathology through the Wnt11/β-catenin signaling pathway axis

Abstract Background Wilforine (WFR) is a monomeric compound of the anti-RA plant Tripterygium wilfordii Hook. f. (TwHF). Whether WFR has anti-RA effect, its molecular mechanism has not been elucidated. Aim of the study Our study aims to clarify how WFR inhibits fibroblast-like synovial cells (FLS) a...

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Bibliographic Details
Main Authors:	Yurong Huang, Yanhui Peng, Hui Li, Chen Li, Yajie Wu, Xiaomei Wang, Jun Chang, Chenggui Miao
Format:	Article
Language:	English
Published:	BMC 2023-12-01
Series:	Arthritis Research & Therapy
Subjects:	Rheumatoid arthritis Fibroblast-like synoviocytes Wilforine Tripterygium wilfordii Hook. f. Wnt11/β-catenin signaling pathway
Online Access:	https://doi.org/10.1186/s13075-023-03224-2

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