Comprehensive landscape of neutralizing antibody and cell-mediated response elicited by the 1/5 fractional dose of 17DD-YF primary vaccination in adults

Comprehensive landscape of neutralizing antibody and cell-mediated response elicited by the 1/5 fractional dose of 17DD-YF primary vaccination in adults

Abstract The present study aimed at evaluating the YF-specific neutralizing antibody profile besides a multiparametric analysis of phenotypic/functional features of cell-mediated response elicited by the 1/5 fractional dose of 17DD-YF vaccine, administered as a single subcutaneous injection. The imm...

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Bibliographic Details
Main Authors: Laise Rodrigues Reis, Ismael Artur Costa-Rocha, Thais Abdala-Torres, Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhães, Márcio Sobreira Silva Araújo, Elaine Spezialli, Lis Ribeiro do Valle Antonelli, Rosiane Aparecida da Silva-Pereira, Gregório Guilherme Almeida, Eder Gatti Fernandes, Francieli Fontana Sutile Tardetti Fantinato, Carla Magda Allan Santos Domingues, Maria Cristina Ferreira Lemos, Alexandre Chieppe, Jandira Aparecida Campos Lemos, Jordana Grazziela Coelho-dos-Reis, Sheila Maria Barbosa de Lima, Adriana de Souza Azevedo, Waleska Dias Schwarcz, Luiz Antônio Bastos Camacho, Maria de Lourdes de Sousa Maia, Tatiana Guimarães de Noronha, Caroline Duault, Yael Rosenberg-Hasson, Andréa Teixeira-Carvalho, Holden Terry Maecker, Olindo Assis Martins-Filho, Collaborative Group for Studies of Yellow Fever Vaccine
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Yellow fever
17DD vaccine
Fractional dose
Neutralizing antibodies
Cellular memory
Adults
Online Access:https://doi.org/10.1038/s41598-024-57645-3

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