Modeling of Ca2+ transients initiated by GPCR agonists in mesenchymal stromal cells

Modeling of Ca2+ transients initiated by GPCR agonists in mesenchymal stromal cells

The integrative study that included experimentation and mathematical modeling was carried out to analyze dynamic aspects of transient Ca2+ signaling induced by brief pulses of GPCR agonists in mesenchymal stromal cells from the human adipose tissue (AD-MSCs). The experimental findings argued for IP3...

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Bibliographic Details
Main Authors: Nikolai P. Kaimachnikov, Polina D. Kotova, Ekaterina N. Kochkina, Olga A. Rogachevskaja, Alexander A. Khokhlov, Marina F. Bystrova, Stanislav S. Kolesnikov
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:BBA Advances
Subjects:
Agonist-induced Ca2+ signaling
IP3 receptors
Ca2+-induced Ca2+ release
Mathematical modeling
Mesenchymal stromal cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2667160321000119

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http://www.sciencedirect.com/science/article/pii/S2667160321000119

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