Antibacterial Activity of Vanillic Acid against Staphylococcus aureus, Salmonella typhi, and Proteus mirabilis
Aim. This study investigated the efficacy of vanillic acid against selected pathogenic bacteria obtained from clinical samples. Method. The antibacterial efficacy of vanillic acid against selected pathogenic bacteria collected from clinical samples was studied using a broth macrodilution method. Th...
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| Format: | Article |
| Language: | English |
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Universidad Nacional Hermilio Valdizán de Huánuco
2022-12-01
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| Series: | Microbes, Infection and Chemotherapy |
| Subjects: | |
| Online Access: | https://revistas.unheval.edu.pe/index.php/mic/article/view/1548 |
| _version_ | 1811315841656946688 |
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| author | Hafeez Adekola Abdulwasiu O. Adeleye Titilayo O. Adesetan Jamiu B. Folorunso Festus A. Odeyemi |
| author_facet | Hafeez Adekola Abdulwasiu O. Adeleye Titilayo O. Adesetan Jamiu B. Folorunso Festus A. Odeyemi |
| author_sort | Hafeez Adekola |
| collection | DOAJ |
| description |
Aim. This study investigated the efficacy of vanillic acid against selected pathogenic bacteria obtained from clinical samples. Method. The antibacterial efficacy of vanillic acid against selected pathogenic bacteria collected from clinical samples was studied using a broth macrodilution method. The minimum inhibitory concentration was determined by treating each isolate with increasing amounts of vanillic acid ranging from 150 to 2000 µg/ml. Results. The lowest inhibitory concentrations found were 600 µg/ml for Staphylococcus aureus, Proteus mirabilis, and Salmonella Typhi, and the time-kill susceptibility test also demonstrated a significant reduction in viable cells of the bacterial isolates investigated in this study. The findings of this study confirmed the antimicrobial effect of vanillic acid on bacterial growth and its activity against Staphylococcus aureus, Proteus mirabilis, and Salmonella Typhi. Conclusion. Vanillic acid may provide a solution for alternate therapeutic choices for diseases caused by Staphylococcus aureus, Proteus mirabilis, and Salmonella Typhi.
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| first_indexed | 2024-04-13T11:38:31Z |
| format | Article |
| id | doaj.art-68c9106264484b29b24409557f4b432e |
| institution | Directory Open Access Journal |
| issn | 2789-4274 |
| language | English |
| last_indexed | 2024-04-13T11:38:31Z |
| publishDate | 2022-12-01 |
| publisher | Universidad Nacional Hermilio Valdizán de Huánuco |
| record_format | Article |
| series | Microbes, Infection and Chemotherapy |
| spelling | doaj.art-68c9106264484b29b24409557f4b432e2022-12-22T02:48:22ZengUniversidad Nacional Hermilio Valdizán de HuánucoMicrobes, Infection and Chemotherapy2789-42742022-12-01210.54034/mic.e1548Antibacterial Activity of Vanillic Acid against Staphylococcus aureus, Salmonella typhi, and Proteus mirabilisHafeez Adekola0Abdulwasiu O. Adeleye1Titilayo O. Adesetan2Jamiu B. Folorunso3Festus A. Odeyemi4Department of Microbiology, Olabisi Onabanjo University, Ago-Iwoye, Ogun State, NigeriaDepartment of Biochemistry, Federal University of Agriculture, Abeokuta, Ogun State, NigeriaDepartment of Microbiology, Olabisi Onabanjo University, Ago-Iwoye, Ogun State, NigeriaDepartment of Medical Laboratory, Health Services Directorate, Olabisi Onabanjo University, Ago-Iwoye, Ogun State, NigeriaDepartment of Medical Laboratory, Health Services Directorate, Olabisi Onabanjo University, Ago-Iwoye, Ogun State, Nigeria Aim. This study investigated the efficacy of vanillic acid against selected pathogenic bacteria obtained from clinical samples. Method. The antibacterial efficacy of vanillic acid against selected pathogenic bacteria collected from clinical samples was studied using a broth macrodilution method. The minimum inhibitory concentration was determined by treating each isolate with increasing amounts of vanillic acid ranging from 150 to 2000 µg/ml. Results. The lowest inhibitory concentrations found were 600 µg/ml for Staphylococcus aureus, Proteus mirabilis, and Salmonella Typhi, and the time-kill susceptibility test also demonstrated a significant reduction in viable cells of the bacterial isolates investigated in this study. The findings of this study confirmed the antimicrobial effect of vanillic acid on bacterial growth and its activity against Staphylococcus aureus, Proteus mirabilis, and Salmonella Typhi. Conclusion. Vanillic acid may provide a solution for alternate therapeutic choices for diseases caused by Staphylococcus aureus, Proteus mirabilis, and Salmonella Typhi. https://revistas.unheval.edu.pe/index.php/mic/article/view/1548vanillic acidantimicrobialbacteriaMIC |
| spellingShingle | Hafeez Adekola Abdulwasiu O. Adeleye Titilayo O. Adesetan Jamiu B. Folorunso Festus A. Odeyemi Antibacterial Activity of Vanillic Acid against Staphylococcus aureus, Salmonella typhi, and Proteus mirabilis Microbes, Infection and Chemotherapy vanillic acid antimicrobial bacteria MIC |
| title | Antibacterial Activity of Vanillic Acid against Staphylococcus aureus, Salmonella typhi, and Proteus mirabilis |
| title_full | Antibacterial Activity of Vanillic Acid against Staphylococcus aureus, Salmonella typhi, and Proteus mirabilis |
| title_fullStr | Antibacterial Activity of Vanillic Acid against Staphylococcus aureus, Salmonella typhi, and Proteus mirabilis |
| title_full_unstemmed | Antibacterial Activity of Vanillic Acid against Staphylococcus aureus, Salmonella typhi, and Proteus mirabilis |
| title_short | Antibacterial Activity of Vanillic Acid against Staphylococcus aureus, Salmonella typhi, and Proteus mirabilis |
| title_sort | antibacterial activity of vanillic acid against staphylococcus aureus salmonella typhi and proteus mirabilis |
| topic | vanillic acid antimicrobial bacteria MIC |
| url | https://revistas.unheval.edu.pe/index.php/mic/article/view/1548 |
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