Genome sequencing and analysis of <it>Salmonella enterica</it> serovar Typhi strain CR0063 representing a carrier individual during an outbreak of typhoid fever in Kelantan, Malaysia
<p>Abstract</p> <p><it>Salmonella</it> Typhi is a human restricted pathogen with a significant number of individuals as asymptomatic carriers of the bacterium. <it>Salmonella</it> infection can be effectively controlled if a reliable method for identificatio...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2012-12-01
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| Series: | Gut Pathogens |
| Online Access: | http://www.gutpathogens.com/content/4/1/20 |
| _version_ | 1818361789360898048 |
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| author | Baddam Ramani Kumar Narender Shaik Sabiha Suma Tiruvayipati Ngoi Soo Thong Kwai-Lin Ahmed Niyaz |
| author_facet | Baddam Ramani Kumar Narender Shaik Sabiha Suma Tiruvayipati Ngoi Soo Thong Kwai-Lin Ahmed Niyaz |
| author_sort | Baddam Ramani |
| collection | DOAJ |
| description | <p>Abstract</p> <p><it>Salmonella</it> Typhi is a human restricted pathogen with a significant number of individuals as asymptomatic carriers of the bacterium. <it>Salmonella</it> infection can be effectively controlled if a reliable method for identification of these carriers is developed. In this context, the availability of whole genomes of carrier strains through high- throughput sequencing and further downstream analysis by comparative genomics approaches is very promising. Herein we describe the genome sequence of a <it>Salmonella</it> Typhi isolate representing an asymptomatic carrier individual during a prolonged outbreak of typhoid fever in Kelantan, Malaysia. Putative genomic coordinates relevant in pathogenesis and persistence of this carrier strain are identified and discussed.</p> |
| first_indexed | 2024-12-13T21:22:16Z |
| format | Article |
| id | doaj.art-68c9e51f366b4bc382c6b52c435dc5bf |
| institution | Directory Open Access Journal |
| issn | 1757-4749 |
| language | English |
| last_indexed | 2024-12-13T21:22:16Z |
| publishDate | 2012-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Gut Pathogens |
| spelling | doaj.art-68c9e51f366b4bc382c6b52c435dc5bf2022-12-21T23:31:04ZengBMCGut Pathogens1757-47492012-12-01412010.1186/1757-4749-4-20Genome sequencing and analysis of <it>Salmonella enterica</it> serovar Typhi strain CR0063 representing a carrier individual during an outbreak of typhoid fever in Kelantan, MalaysiaBaddam RamaniKumar NarenderShaik SabihaSuma TiruvayipatiNgoi SooThong Kwai-LinAhmed Niyaz<p>Abstract</p> <p><it>Salmonella</it> Typhi is a human restricted pathogen with a significant number of individuals as asymptomatic carriers of the bacterium. <it>Salmonella</it> infection can be effectively controlled if a reliable method for identification of these carriers is developed. In this context, the availability of whole genomes of carrier strains through high- throughput sequencing and further downstream analysis by comparative genomics approaches is very promising. Herein we describe the genome sequence of a <it>Salmonella</it> Typhi isolate representing an asymptomatic carrier individual during a prolonged outbreak of typhoid fever in Kelantan, Malaysia. Putative genomic coordinates relevant in pathogenesis and persistence of this carrier strain are identified and discussed.</p>http://www.gutpathogens.com/content/4/1/20 |
| spellingShingle | Baddam Ramani Kumar Narender Shaik Sabiha Suma Tiruvayipati Ngoi Soo Thong Kwai-Lin Ahmed Niyaz Genome sequencing and analysis of <it>Salmonella enterica</it> serovar Typhi strain CR0063 representing a carrier individual during an outbreak of typhoid fever in Kelantan, Malaysia Gut Pathogens |
| title | Genome sequencing and analysis of <it>Salmonella enterica</it> serovar Typhi strain CR0063 representing a carrier individual during an outbreak of typhoid fever in Kelantan, Malaysia |
| title_full | Genome sequencing and analysis of <it>Salmonella enterica</it> serovar Typhi strain CR0063 representing a carrier individual during an outbreak of typhoid fever in Kelantan, Malaysia |
| title_fullStr | Genome sequencing and analysis of <it>Salmonella enterica</it> serovar Typhi strain CR0063 representing a carrier individual during an outbreak of typhoid fever in Kelantan, Malaysia |
| title_full_unstemmed | Genome sequencing and analysis of <it>Salmonella enterica</it> serovar Typhi strain CR0063 representing a carrier individual during an outbreak of typhoid fever in Kelantan, Malaysia |
| title_short | Genome sequencing and analysis of <it>Salmonella enterica</it> serovar Typhi strain CR0063 representing a carrier individual during an outbreak of typhoid fever in Kelantan, Malaysia |
| title_sort | genome sequencing and analysis of it salmonella enterica it serovar typhi strain cr0063 representing a carrier individual during an outbreak of typhoid fever in kelantan malaysia |
| url | http://www.gutpathogens.com/content/4/1/20 |
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