Understanding patterns of HIV multi-drug resistance through models of temporal and spatial drug heterogeneity
Triple-drug therapies have transformed HIV from a fatal condition to a chronic one. These therapies should prevent HIV drug resistance evolution, because one or more drugs suppress any partially resistant viruses. In practice, such therapies drastically reduced, but did not eliminate, resistance evo...
Main Authors: | Alison F Feder, Kristin N Harper, Chanson J Brumme, Pleuni S Pennings |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/69032 |
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