Contemporary Management of Severely Calcified Coronary Lesions

Coronary artery calcification is increasingly prevalent in our patient population. It significantly limits the procedural success of percutaneous coronary intervention and is associated with a higher risk of adverse cardiovascular events both in the short-term and long-term. There are several modali...

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Main Authors: Natthapon Angsubhakorn, Nicolas Kang, Colleen Fearon, Chol Techorueangwiwat, Pooja Swamy, Emmanouil S. Brilakis, Aditya S. Bharadwaj
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/12/10/1638
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author Natthapon Angsubhakorn
Nicolas Kang
Colleen Fearon
Chol Techorueangwiwat
Pooja Swamy
Emmanouil S. Brilakis
Aditya S. Bharadwaj
author_facet Natthapon Angsubhakorn
Nicolas Kang
Colleen Fearon
Chol Techorueangwiwat
Pooja Swamy
Emmanouil S. Brilakis
Aditya S. Bharadwaj
author_sort Natthapon Angsubhakorn
collection DOAJ
description Coronary artery calcification is increasingly prevalent in our patient population. It significantly limits the procedural success of percutaneous coronary intervention and is associated with a higher risk of adverse cardiovascular events both in the short-term and long-term. There are several modalities for modifying calcified plaque, such as balloon angioplasty (including specialty balloons), coronary atheroablative therapy (rotational, orbital, and laser atherectomy), and intravascular lithotripsy. We discuss each modality’s relative advantages and disadvantages and the data supporting their use. This review also highlights the importance of intravascular imaging to characterize coronary calcification and presents an algorithm to tailor the calcium modification therapy based on specific coronary lesion characteristics.
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spelling doaj.art-68cbb67262a247b18da793c15f682e9c2023-11-24T00:49:38ZengMDPI AGJournal of Personalized Medicine2075-44262022-10-011210163810.3390/jpm12101638Contemporary Management of Severely Calcified Coronary LesionsNatthapon Angsubhakorn0Nicolas Kang1Colleen Fearon2Chol Techorueangwiwat3Pooja Swamy4Emmanouil S. Brilakis5Aditya S. Bharadwaj6Division of Cardiology, Loma Linda University Medical Center, Loma Linda, CA 92354, USADepartment of Medicine, Loma Linda University Medical Center, Loma Linda, CA 92354, USADivision of Cardiology, Loma Linda University Medical Center, Loma Linda, CA 92354, USADivision of Cardiology, University of California, Riverside, CA 92521, USADivision of Cardiology, Loma Linda University Medical Center, Loma Linda, CA 92354, USAMinneapolis Heart Institute, Abbott Northwestern Hospital and Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USADivision of Cardiology, Loma Linda University Medical Center, Loma Linda, CA 92354, USACoronary artery calcification is increasingly prevalent in our patient population. It significantly limits the procedural success of percutaneous coronary intervention and is associated with a higher risk of adverse cardiovascular events both in the short-term and long-term. There are several modalities for modifying calcified plaque, such as balloon angioplasty (including specialty balloons), coronary atheroablative therapy (rotational, orbital, and laser atherectomy), and intravascular lithotripsy. We discuss each modality’s relative advantages and disadvantages and the data supporting their use. This review also highlights the importance of intravascular imaging to characterize coronary calcification and presents an algorithm to tailor the calcium modification therapy based on specific coronary lesion characteristics.https://www.mdpi.com/2075-4426/12/10/1638coronary artery calcificationintravascular imagingpercutaneous coronary intervention
spellingShingle Natthapon Angsubhakorn
Nicolas Kang
Colleen Fearon
Chol Techorueangwiwat
Pooja Swamy
Emmanouil S. Brilakis
Aditya S. Bharadwaj
Contemporary Management of Severely Calcified Coronary Lesions
Journal of Personalized Medicine
coronary artery calcification
intravascular imaging
percutaneous coronary intervention
title Contemporary Management of Severely Calcified Coronary Lesions
title_full Contemporary Management of Severely Calcified Coronary Lesions
title_fullStr Contemporary Management of Severely Calcified Coronary Lesions
title_full_unstemmed Contemporary Management of Severely Calcified Coronary Lesions
title_short Contemporary Management of Severely Calcified Coronary Lesions
title_sort contemporary management of severely calcified coronary lesions
topic coronary artery calcification
intravascular imaging
percutaneous coronary intervention
url https://www.mdpi.com/2075-4426/12/10/1638
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