Hippocampus-Avoidance Whole-Brain Radiation Therapy Is Efficient in the Long-Term Preservation of Hippocampal Volume

Hippocampus-Avoidance Whole-Brain Radiation Therapy Is Efficient in the Long-Term Preservation of Hippocampal Volume

Background and PurposeWith improved life expectancy, preventing neurocognitive decline after cerebral radiotherapy is gaining more importance. Hippocampal damage has been considered the main culprit for cognitive deficits following conventional whole-brain radiation therapy (WBRT). Here, we aimed to...

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Bibliographic Details
Main Authors: Ilinca Popp, Alexander Rau, Elias Kellner, Marco Reisert, Jamina Tara Fennell, Thomas Rothe, Carsten Nieder, Horst Urbach, Karl Egger, Anca Ligia Grosu, Christoph P. Kaller
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
hippocampus
atrophy
WBRT (whole-brain radiation therapy)
cognitive function
MRI
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.714709/full

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