Resting-state fMRI functional connectivity of the left temporal parietal junction is associated with visual temporal order threshold

Abstract The study aimed to determine the relationship between the millisecond timing, measured by visual temporal order threshold (TOT), i.e. a minimum gap between two successive stimuli necessary to judge a before-after relation, and resting-state fMRI functional connectivity (rsFC). We assume tha...

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Main Authors: Monika Lewandowska, Jan Nikadon, Tomasz Wolak, Krzysztof Tołpa, Tomasz Piotrowski, Mateusz Chojnowski, Joanna Dreszer
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20309-1
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author Monika Lewandowska
Jan Nikadon
Tomasz Wolak
Krzysztof Tołpa
Tomasz Piotrowski
Mateusz Chojnowski
Joanna Dreszer
author_facet Monika Lewandowska
Jan Nikadon
Tomasz Wolak
Krzysztof Tołpa
Tomasz Piotrowski
Mateusz Chojnowski
Joanna Dreszer
author_sort Monika Lewandowska
collection DOAJ
description Abstract The study aimed to determine the relationship between the millisecond timing, measured by visual temporal order threshold (TOT), i.e. a minimum gap between two successive stimuli necessary to judge a before-after relation, and resting-state fMRI functional connectivity (rsFC). We assume that the TOT reflects a relatively stable feature of local internal state networks and is associated with rsFC of the temporal parietal junction (TPJ). Sixty five healthy young adults underwent the visual TOT, fluid intelligence (Gf) and an eyes-open resting-state fMRI examination. After controlling for the influence of gender, the higher the TOT, the stronger was the left TPJ’s rsFC with the left postcentral and the right precentral gyri, bilateral putamen and the right supplementary motor area. When the effects of Gf and TOT × Gf interaction were additionally controlled, the TOT—left TPJ’s rsFC relationship survived for almost all above regions with the exception of the left and right putamen. This is the first study demonstrating that visual TOT is associated with rsFC between the areas involved both in sub-second timing and motor control. Current outcomes indicate that the local neural networks are prepared to process brief, rapidly presented, consecutive events, even in the absence of such stimulation.
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spelling doaj.art-68cef23fdfea43caa396424a15bb8e5d2022-12-22T03:18:02ZengNature PortfolioScientific Reports2045-23222022-09-0112111210.1038/s41598-022-20309-1Resting-state fMRI functional connectivity of the left temporal parietal junction is associated with visual temporal order thresholdMonika Lewandowska0Jan Nikadon1Tomasz Wolak2Krzysztof Tołpa3Tomasz Piotrowski4Mateusz Chojnowski5Joanna Dreszer6Institute of Psychology, Faculty of Philosophy and Social Sciences, Nicolaus Copernicus University in TorunCenter for Research on Social Relations, SWPS University of Social Sciences and HumanitiesBioimaging Research Center, World Hearing Center, Institute of Physiology and Pathology of HearingCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in TorunDepartment of Informatics, Nicolaus Copernicus University in TorunCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in TorunInstitute of Psychology, Faculty of Philosophy and Social Sciences, Nicolaus Copernicus University in TorunAbstract The study aimed to determine the relationship between the millisecond timing, measured by visual temporal order threshold (TOT), i.e. a minimum gap between two successive stimuli necessary to judge a before-after relation, and resting-state fMRI functional connectivity (rsFC). We assume that the TOT reflects a relatively stable feature of local internal state networks and is associated with rsFC of the temporal parietal junction (TPJ). Sixty five healthy young adults underwent the visual TOT, fluid intelligence (Gf) and an eyes-open resting-state fMRI examination. After controlling for the influence of gender, the higher the TOT, the stronger was the left TPJ’s rsFC with the left postcentral and the right precentral gyri, bilateral putamen and the right supplementary motor area. When the effects of Gf and TOT × Gf interaction were additionally controlled, the TOT—left TPJ’s rsFC relationship survived for almost all above regions with the exception of the left and right putamen. This is the first study demonstrating that visual TOT is associated with rsFC between the areas involved both in sub-second timing and motor control. Current outcomes indicate that the local neural networks are prepared to process brief, rapidly presented, consecutive events, even in the absence of such stimulation.https://doi.org/10.1038/s41598-022-20309-1
spellingShingle Monika Lewandowska
Jan Nikadon
Tomasz Wolak
Krzysztof Tołpa
Tomasz Piotrowski
Mateusz Chojnowski
Joanna Dreszer
Resting-state fMRI functional connectivity of the left temporal parietal junction is associated with visual temporal order threshold
Scientific Reports
title Resting-state fMRI functional connectivity of the left temporal parietal junction is associated with visual temporal order threshold
title_full Resting-state fMRI functional connectivity of the left temporal parietal junction is associated with visual temporal order threshold
title_fullStr Resting-state fMRI functional connectivity of the left temporal parietal junction is associated with visual temporal order threshold
title_full_unstemmed Resting-state fMRI functional connectivity of the left temporal parietal junction is associated with visual temporal order threshold
title_short Resting-state fMRI functional connectivity of the left temporal parietal junction is associated with visual temporal order threshold
title_sort resting state fmri functional connectivity of the left temporal parietal junction is associated with visual temporal order threshold
url https://doi.org/10.1038/s41598-022-20309-1
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