Impact of Cesarean Delivery and Breastfeeding on Secretory Immunoglobulin A in the Infant Gut Is Mediated by Gut Microbiota and Metabolites

Impact of Cesarean Delivery and Breastfeeding on Secretory Immunoglobulin A in the Infant Gut Is Mediated by Gut Microbiota and Metabolites

How gut immunity in early life is shaped by birth in relation to delivery mode, intrapartum antibiotic prophylaxis (IAP) and labor remains undetermined. We aimed to address this gap with a study of secretory Immunoglobulin A (SIgA) in the infant gut that also tested SIgA-stimulating pathways mediate...

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Bibliographic Details
Main Authors: Yuan Yao Chen, Hein M. Tun, Catherine J. Field, Piushkumar J. Mandhane, Theo J. Moraes, Elinor Simons, Stuart E. Turvey, Padmaja Subbarao, James A. Scott, Anita L. Kozyrskyj
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Metabolites
Subjects:
birth mode
infant gut microbiota
metabolites
SIgA
Online Access:https://www.mdpi.com/2218-1989/13/2/148

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