Clinical factors affecting functioning in patients with schizophrenia or schizoaffective disorder

Introduction Schizophrenia is often associated with impaired functioning abilities due to its disabling symptoms. Objectives to determine the clinical factors that impact the functioning in stabilized patients withschizophrenia and schizoaffective disorder. Methods We conducted a cross-sectional,...

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Main Authors: C. Neily, N. Charfi, G. Smaoui, N. Feki, R. Omri, L. Zouari, J. Ben Thabet, M. Maâlejboauli, M. Maalej
Format: Article
Language:English
Published: Cambridge University Press 2022-06-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0924933822020156/type/journal_article
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author C. Neily
N. Charfi
G. Smaoui
N. Feki
R. Omri
L. Zouari
J. Ben Thabet
M. Maâlejboauli
M. Maalej
author_facet C. Neily
N. Charfi
G. Smaoui
N. Feki
R. Omri
L. Zouari
J. Ben Thabet
M. Maâlejboauli
M. Maalej
author_sort C. Neily
collection DOAJ
description Introduction Schizophrenia is often associated with impaired functioning abilities due to its disabling symptoms. Objectives to determine the clinical factors that impact the functioning in stabilized patients withschizophrenia and schizoaffective disorder. Methods We conducted a cross-sectional, descriptive and analytical study. It was carried out on an outpatient population with schizophrenia or schizoaffective disorder diagnosis. We used the Functional Assessment Staging Scale (FAST) to measure the functional capacity, the PANSS to assess psychosis symptom severity and the Calgary scale to screen for comorbid depression. Results Seventy-five patients were included with 61 males (81.3%).The mean age was 39.81 ± 9.96 years. The mean sore of the Fast scale was 33 ± 14.95. 90% of our patients scored higher than 11 on the FAST scale revealing a functioning deficiency. 18.7% scored higher than 6 on the Calgary scale revealing a comorbid depression .No significant correlations were found between the FAST score and the age of patient, the gender,the age of onset of psychosis, the duration of untreated psychosis and the number of life-time episodes. Scores of PANSS were significantly higher among patients with a functioning deficiency (p<0.00).No significant correlation was found between the FAST score and the Calgary score. Conclusions Our study suggests that the severity of residual positive and negative symptoms affects negatively the functioning of patients with schizophrenia or schizoaffective disorder. Thus, targeting those symptoms in the treatment may have significant functional benefits. Disclosure No significant relationships.
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spelling doaj.art-68d4513afc8048cf89bf6e22bb2ea7a42023-11-17T05:07:08ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S780S78010.1192/j.eurpsy.2022.2015Clinical factors affecting functioning in patients with schizophrenia or schizoaffective disorderC. Neily0N. Charfi1G. Smaoui2N. Feki3R. Omri4L. Zouari5J. Ben Thabet6M. Maâlejboauli7M. Maalej8Hedi Chaker hospital, Psychiatry Department, Sfax, TunisiaHedi Chaker hospital, Psychiatry Department, Sfax, TunisiaHedi Chaker hospital, Psychiatry Department, Sfax, TunisiaHedi Chaker hospital, Psychiatry Department, Sfax, TunisiaHedi Chaker hospital, Psychiatry Department, Sfax, TunisiaHedi Chaker hospital, Psychiatry Department, Sfax, TunisiaHedi Chaker hospital, Psychiatry Department, Sfax, TunisiaHedi Chaker hospital, Psychiatry Department, Sfax, TunisiaHedi Chaker hospital, Psychiatry Department, Sfax, Tunisia Introduction Schizophrenia is often associated with impaired functioning abilities due to its disabling symptoms. Objectives to determine the clinical factors that impact the functioning in stabilized patients withschizophrenia and schizoaffective disorder. Methods We conducted a cross-sectional, descriptive and analytical study. It was carried out on an outpatient population with schizophrenia or schizoaffective disorder diagnosis. We used the Functional Assessment Staging Scale (FAST) to measure the functional capacity, the PANSS to assess psychosis symptom severity and the Calgary scale to screen for comorbid depression. Results Seventy-five patients were included with 61 males (81.3%).The mean age was 39.81 ± 9.96 years. The mean sore of the Fast scale was 33 ± 14.95. 90% of our patients scored higher than 11 on the FAST scale revealing a functioning deficiency. 18.7% scored higher than 6 on the Calgary scale revealing a comorbid depression .No significant correlations were found between the FAST score and the age of patient, the gender,the age of onset of psychosis, the duration of untreated psychosis and the number of life-time episodes. Scores of PANSS were significantly higher among patients with a functioning deficiency (p<0.00).No significant correlation was found between the FAST score and the Calgary score. Conclusions Our study suggests that the severity of residual positive and negative symptoms affects negatively the functioning of patients with schizophrenia or schizoaffective disorder. Thus, targeting those symptoms in the treatment may have significant functional benefits. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822020156/type/journal_articlefunctioningschizophrénia
spellingShingle C. Neily
N. Charfi
G. Smaoui
N. Feki
R. Omri
L. Zouari
J. Ben Thabet
M. Maâlejboauli
M. Maalej
Clinical factors affecting functioning in patients with schizophrenia or schizoaffective disorder
European Psychiatry
functioning
schizophrénia
title Clinical factors affecting functioning in patients with schizophrenia or schizoaffective disorder
title_full Clinical factors affecting functioning in patients with schizophrenia or schizoaffective disorder
title_fullStr Clinical factors affecting functioning in patients with schizophrenia or schizoaffective disorder
title_full_unstemmed Clinical factors affecting functioning in patients with schizophrenia or schizoaffective disorder
title_short Clinical factors affecting functioning in patients with schizophrenia or schizoaffective disorder
title_sort clinical factors affecting functioning in patients with schizophrenia or schizoaffective disorder
topic functioning
schizophrénia
url https://www.cambridge.org/core/product/identifier/S0924933822020156/type/journal_article
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