A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM)
BACKGROUND AND OBJECTIVE: Intracellular magnesium is a cofactor for several enzymes in carbohydrate metabolism. The aim of this study is to demonstrate the role of magnesium as an effective and an underlying factor in disrupted glucose metabolism among pregnant women with and without gestational dia...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2016-12-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| Subjects: | |
| Online Access: | http://jbums.org/browse.php?a_code=A-10-2165-1&slc_lang=en&sid=1 |
| _version_ | 1818701200323772416 |
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| author | ZA Bouzari F Elmi S Esmaeilzadeh Sh Yazdani M Naeimi rad M R Nadimi Barforoushi Z Moazzezi K Hajian |
| author_facet | ZA Bouzari F Elmi S Esmaeilzadeh Sh Yazdani M Naeimi rad M R Nadimi Barforoushi Z Moazzezi K Hajian |
| author_sort | ZA Bouzari |
| collection | DOAJ |
| description | BACKGROUND AND OBJECTIVE: Intracellular magnesium is a cofactor for several enzymes in carbohydrate metabolism. The aim of this study is to demonstrate the role of magnesium as an effective and an underlying factor in disrupted glucose metabolism among pregnant women with and without gestational diabetes mellitus (GDM).
METHODS: This cross-sectional was conducted among 24-32 weeks pregnant women admitted to gynecology clinic of Ayatollah Rohani Hospital in Babol. Patients were divided into four groups: healthy pregnant women, pregnant women with high-risk gestational diabetes, pregnant women with gestational diabetes mellitus and pregnant women with overt diabetes. The demographic information was gathered using a questionnaire and the serum level, magnesium RBC and the fasting blood sugar were measured by laboratory methods and were compared between the four groups.
FINDINGS: 399 patients with mean age of 26.53±5.54 participated in this study. Overall, mean serum magnesium level was 1.71±0.12 mg/dL and magnesium level in RBC was 4.88±0.29 mg/dL. The mean serum magnesium level was 1.73±0.10 in healthy pregnant women, 1.73±0.12 in pregnant women with high-risk gestational diabetes, 1.71±0.13 in pregnant women with gestational diabetes mellitus and 1.64±0.15 in pregnant women with overt diabetes and there was a significant difference between the four groups (p=0.001). The result regarding RBC magnesium level was found to be 5.12±0.18, 4.81±0.23, 4.77±0.24 and 4.66±0.38 in healthy pregnant women, pregnant women with high-risk gestational diabetes, pregnant women with gestational diabetes mellitus and pregnant women with overt diabetes, respectively, which was significant (p=0.001). Serum level and RBC magnesium in diabetic women was less than non-diabetic women.
CONCLUSION: Results of the study demonstrated that magnesium could be an effective and an underlying factor in identification of disrupted glucose metabolism in pregnant women. |
| first_indexed | 2024-12-17T15:17:03Z |
| format | Article |
| id | doaj.art-68d4e14c25af4cec83bd32a7960a252c |
| institution | Directory Open Access Journal |
| issn | 1561-4107 2251-7170 |
| language | English |
| last_indexed | 2024-12-17T15:17:03Z |
| publishDate | 2016-12-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| spelling | doaj.art-68d4e14c25af4cec83bd32a7960a252c2022-12-21T21:43:30ZengBabol University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul1561-41072251-71702016-12-0118127175A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM)ZA Bouzari0F Elmi1S Esmaeilzadeh2Sh Yazdani3M Naeimi rad4M R Nadimi Barforoushi5Z Moazzezi6K Hajian7 Cellular & Molecular Biology Research Center, Health Research Institute, Babol of University of Medical Science, Babol, I.R.Iran Student Committee Research, Babol University of Medical Sciences, Babol, I.R.Iran Fateme Zahra Fertility & Infertility Research Health Center, Health Research Institute, Babol of University of Medical Science, Babol, I.R.Iran Fateme Zahra Fertility & Infertility Research Health Center, Health Research Institute, Babol of University of Medical Science, Babol, I.R.Iran Clinical Research Development Center, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, I.R.Iran. Islamic Azad University of Damghan, Damghan, I.R.Iran Department of Internal Medicine, Babol University of Medical Sciences, Babol, I.R.Iran Department of Statistic and Epidemiology, Babol University of Medical Sciences, Babol, I.R.Iran BACKGROUND AND OBJECTIVE: Intracellular magnesium is a cofactor for several enzymes in carbohydrate metabolism. The aim of this study is to demonstrate the role of magnesium as an effective and an underlying factor in disrupted glucose metabolism among pregnant women with and without gestational diabetes mellitus (GDM). METHODS: This cross-sectional was conducted among 24-32 weeks pregnant women admitted to gynecology clinic of Ayatollah Rohani Hospital in Babol. Patients were divided into four groups: healthy pregnant women, pregnant women with high-risk gestational diabetes, pregnant women with gestational diabetes mellitus and pregnant women with overt diabetes. The demographic information was gathered using a questionnaire and the serum level, magnesium RBC and the fasting blood sugar were measured by laboratory methods and were compared between the four groups. FINDINGS: 399 patients with mean age of 26.53±5.54 participated in this study. Overall, mean serum magnesium level was 1.71±0.12 mg/dL and magnesium level in RBC was 4.88±0.29 mg/dL. The mean serum magnesium level was 1.73±0.10 in healthy pregnant women, 1.73±0.12 in pregnant women with high-risk gestational diabetes, 1.71±0.13 in pregnant women with gestational diabetes mellitus and 1.64±0.15 in pregnant women with overt diabetes and there was a significant difference between the four groups (p=0.001). The result regarding RBC magnesium level was found to be 5.12±0.18, 4.81±0.23, 4.77±0.24 and 4.66±0.38 in healthy pregnant women, pregnant women with high-risk gestational diabetes, pregnant women with gestational diabetes mellitus and pregnant women with overt diabetes, respectively, which was significant (p=0.001). Serum level and RBC magnesium in diabetic women was less than non-diabetic women. CONCLUSION: Results of the study demonstrated that magnesium could be an effective and an underlying factor in identification of disrupted glucose metabolism in pregnant women.http://jbums.org/browse.php?a_code=A-10-2165-1&slc_lang=en&sid=1Magnesium Diabetes Pregnancy Glucose |
| spellingShingle | ZA Bouzari F Elmi S Esmaeilzadeh Sh Yazdani M Naeimi rad M R Nadimi Barforoushi Z Moazzezi K Hajian A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM) Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul Magnesium Diabetes Pregnancy Glucose |
| title | A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM) |
| title_full | A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM) |
| title_fullStr | A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM) |
| title_full_unstemmed | A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM) |
| title_short | A Comparison of Serum Magnesium Level in Pregnant Women with and without Gestational Diabetes Mellitus (GDM) |
| title_sort | comparison of serum magnesium level in pregnant women with and without gestational diabetes mellitus gdm |
| topic | Magnesium Diabetes Pregnancy Glucose |
| url | http://jbums.org/browse.php?a_code=A-10-2165-1&slc_lang=en&sid=1 |
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