Mechanical ventilation induces brainstem inflammation in preterm fetal sheep

Mechanical ventilation induces brainstem inflammation in preterm fetal sheep

BackgroundPreterm infants have immature respiratory drive and often require prolonged periods of mechanical ventilation. Prolonged mechanical ventilation induces systemic inflammation resulting in ventilation-induced brain injury, however its effect on brainstem respiratory centers is unknown. We ai...

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Bibliographic Details
Main Authors: Kayla Vidinopoulos, Zahrah Azman, Ainsley Somers, Valerie A. Zahra, Alison Thiel, Hui Lu, Yen Pham, Nhi Thao Tran, Beth J. Allison, Eric Herlenius, Stuart Hooper, Robert Galinsky, Graeme R. Polglase
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pediatrics
Subjects:
brainstem
mechanical ventilation
ventilation-induced brain injury
inflammation
preterm birth
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1225294/full

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