Serum Levels of Minerals and Vitamins in Women of Reproductive Age with/without COVID-19: A Case-Control Study

Background and purpose: Vitamins and minerals play an important role in boosting the immune system, and their poor condition in the body leads to reduced resistance to infections such as COVID-19. In the present study, we aimed at examining and comparing the levels of minerals (iron, zinc, copper, a...

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Main Authors: Zoliekha Atarod, Noushin Gordani, Leila Kiani, Mahmood Moosazadeh, Saeid Abedian Kenari
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2022-09-01
Series:Journal of Mazandaran University of Medical Sciences
Subjects:
Online Access:http://jmums.mazums.ac.ir/article-1-18021-en.html
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author Zoliekha Atarod
Noushin Gordani
Leila Kiani
Mahmood Moosazadeh
Saeid Abedian Kenari
author_facet Zoliekha Atarod
Noushin Gordani
Leila Kiani
Mahmood Moosazadeh
Saeid Abedian Kenari
author_sort Zoliekha Atarod
collection DOAJ
description Background and purpose: Vitamins and minerals play an important role in boosting the immune system, and their poor condition in the body leads to reduced resistance to infections such as COVID-19. In the present study, we aimed at examining and comparing the levels of minerals (iron, zinc, copper, and magnesium) and vitamins (B12, D) in women of reproductive age with COVID-19 and healthy women. Materials and methods: This case-control study was performed in 140 women of reproductive age attending Sari Imam Khomeini Hospital and Qaemshahr Razi Hospital selected via convenience sampling in 2020-2021. The participants included 70 women with COVID-19 and 70 healthy women who were matched according to age groups. Blood sampling was done in all groups and the levels of minerals and vitamins were measured using standard kits. Data were analyzed using t-test and Chi-square. Results: Most women in both groups were over 35 years of age and multiparous. Vitamin D levels in both groups were insufficient but was higher in women with COVID-19 than healthy women (P=0.03). Vitamin B12 and copper levels in women with COVID-19 were higher than those in healthy women (P<0.001). Magnesium levels were found to be lower in women with COVID-19 than that in healthy women (P<0.001). Iron and zinc levels were lower in women with COVID-19 than healthy women (P=0.09 and P=0.44), respectively. Conclusion: Due to the insufficient levels of vitamin D in both groups, interventions are necessary to improve this condition. Also, further studies with larger sample size and considering interfering factors are needed to accurately assess the role of vitamins and minerals in COVID-19 and other infections.
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spelling doaj.art-68d80b115a7a4c2d9395311b5363f8e92023-02-28T09:08:23ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792022-09-01322126576Serum Levels of Minerals and Vitamins in Women of Reproductive Age with/without COVID-19: A Case-Control StudyZoliekha Atarod0Noushin Gordani1Leila Kiani2Mahmood Moosazadeh3Saeid Abedian Kenari4 Associate Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran MSc in Counseling in Midwifery, Mazandaran University of Medical Sciences, Sari, Iran Resident in Obstetrics and Gynecology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran Professor, Department of Immunology, Immunogenetics Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: Vitamins and minerals play an important role in boosting the immune system, and their poor condition in the body leads to reduced resistance to infections such as COVID-19. In the present study, we aimed at examining and comparing the levels of minerals (iron, zinc, copper, and magnesium) and vitamins (B12, D) in women of reproductive age with COVID-19 and healthy women. Materials and methods: This case-control study was performed in 140 women of reproductive age attending Sari Imam Khomeini Hospital and Qaemshahr Razi Hospital selected via convenience sampling in 2020-2021. The participants included 70 women with COVID-19 and 70 healthy women who were matched according to age groups. Blood sampling was done in all groups and the levels of minerals and vitamins were measured using standard kits. Data were analyzed using t-test and Chi-square. Results: Most women in both groups were over 35 years of age and multiparous. Vitamin D levels in both groups were insufficient but was higher in women with COVID-19 than healthy women (P=0.03). Vitamin B12 and copper levels in women with COVID-19 were higher than those in healthy women (P<0.001). Magnesium levels were found to be lower in women with COVID-19 than that in healthy women (P<0.001). Iron and zinc levels were lower in women with COVID-19 than healthy women (P=0.09 and P=0.44), respectively. Conclusion: Due to the insufficient levels of vitamin D in both groups, interventions are necessary to improve this condition. Also, further studies with larger sample size and considering interfering factors are needed to accurately assess the role of vitamins and minerals in COVID-19 and other infections.http://jmums.mazums.ac.ir/article-1-18021-en.htmlmineralsvitaminswomen of fertility agecovid-19
spellingShingle Zoliekha Atarod
Noushin Gordani
Leila Kiani
Mahmood Moosazadeh
Saeid Abedian Kenari
Serum Levels of Minerals and Vitamins in Women of Reproductive Age with/without COVID-19: A Case-Control Study
Journal of Mazandaran University of Medical Sciences
minerals
vitamins
women of fertility age
covid-19
title Serum Levels of Minerals and Vitamins in Women of Reproductive Age with/without COVID-19: A Case-Control Study
title_full Serum Levels of Minerals and Vitamins in Women of Reproductive Age with/without COVID-19: A Case-Control Study
title_fullStr Serum Levels of Minerals and Vitamins in Women of Reproductive Age with/without COVID-19: A Case-Control Study
title_full_unstemmed Serum Levels of Minerals and Vitamins in Women of Reproductive Age with/without COVID-19: A Case-Control Study
title_short Serum Levels of Minerals and Vitamins in Women of Reproductive Age with/without COVID-19: A Case-Control Study
title_sort serum levels of minerals and vitamins in women of reproductive age with without covid 19 a case control study
topic minerals
vitamins
women of fertility age
covid-19
url http://jmums.mazums.ac.ir/article-1-18021-en.html
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AT noushingordani serumlevelsofmineralsandvitaminsinwomenofreproductiveagewithwithoutcovid19acasecontrolstudy
AT leilakiani serumlevelsofmineralsandvitaminsinwomenofreproductiveagewithwithoutcovid19acasecontrolstudy
AT mahmoodmoosazadeh serumlevelsofmineralsandvitaminsinwomenofreproductiveagewithwithoutcovid19acasecontrolstudy
AT saeidabediankenari serumlevelsofmineralsandvitaminsinwomenofreproductiveagewithwithoutcovid19acasecontrolstudy