BE4max and AncBE4max Are Efficient in Germline Conversion of C:G to T:A Base Pairs in Zebrafish
The ease of use and robustness of genome editing by CRISPR/Cas9 has led to successful use of gene knockout zebrafish for disease modeling. However, it still remains a challenge to precisely edit the zebrafish genome to create single-nucleotide substitutions, which account for ~60% of human disease-c...
| Main Authors: | , , |
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| 格式: | 文件 |
| 语言: | English |
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MDPI AG
2020-07-01
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| 丛编: | Cells |
| 主题: | |
| 在线阅读: | https://www.mdpi.com/2073-4409/9/7/1690 |