Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease
Inflammatory Bowel Diseases (IBD) are an immune mediated chronic or relapsing disorders of the gastrointestinal (GI) tract. IBD is characterized by a chronic intestinal inflammatory process with various components contributing to the pathogenesis of the disease including environmental factors such a...
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Format: | Article |
Language: | English |
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MDPI AG
2010-04-01
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Series: | Pharmaceuticals |
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Online Access: | http://www.mdpi.com/1424-8247/3/4/1084/ |
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author | Amir Klein Rami Eliakim |
author_facet | Amir Klein Rami Eliakim |
author_sort | Amir Klein |
collection | DOAJ |
description | Inflammatory Bowel Diseases (IBD) are an immune mediated chronic or relapsing disorders of the gastrointestinal (GI) tract. IBD is characterized by a chronic intestinal inflammatory process with various components contributing to the pathogenesis of the disease including environmental factors such as smoking or use of Non Steroidal Anti-Inflammatory Drugs (NSAIDS). NSAIDS are among the most commonly used medications for the treatment of various inflammatory conditions. The main factor limiting NSAIDS use is the concern for the development of gastrointestinal toxicity including mucosal injury. A possible association between the use of NSAIDS and the onset or relapse of IBD has been repeatedly suggested. This article will review the current concepts and evidence of the relationship between IBD and NSAIDS. |
first_indexed | 2024-12-18T17:21:44Z |
format | Article |
id | doaj.art-68dea862441d4309b600a099c0f8b8d8 |
institution | Directory Open Access Journal |
issn | 1424-8247 |
language | English |
last_indexed | 2024-12-18T17:21:44Z |
publishDate | 2010-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Pharmaceuticals |
spelling | doaj.art-68dea862441d4309b600a099c0f8b8d82022-12-21T20:59:48ZengMDPI AGPharmaceuticals1424-82472010-04-01341084109210.3390/ph3041084Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel DiseaseAmir KleinRami EliakimInflammatory Bowel Diseases (IBD) are an immune mediated chronic or relapsing disorders of the gastrointestinal (GI) tract. IBD is characterized by a chronic intestinal inflammatory process with various components contributing to the pathogenesis of the disease including environmental factors such as smoking or use of Non Steroidal Anti-Inflammatory Drugs (NSAIDS). NSAIDS are among the most commonly used medications for the treatment of various inflammatory conditions. The main factor limiting NSAIDS use is the concern for the development of gastrointestinal toxicity including mucosal injury. A possible association between the use of NSAIDS and the onset or relapse of IBD has been repeatedly suggested. This article will review the current concepts and evidence of the relationship between IBD and NSAIDS.http://www.mdpi.com/1424-8247/3/4/1084/NSAIDsIBDCrohn'sUlcerative Colitis |
spellingShingle | Amir Klein Rami Eliakim Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease Pharmaceuticals NSAIDs IBD Crohn's Ulcerative Colitis |
title | Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease |
title_full | Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease |
title_fullStr | Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease |
title_full_unstemmed | Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease |
title_short | Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease |
title_sort | non steroidal anti inflammatory drugs and inflammatory bowel disease |
topic | NSAIDs IBD Crohn's Ulcerative Colitis |
url | http://www.mdpi.com/1424-8247/3/4/1084/ |
work_keys_str_mv | AT amirklein nonsteroidalantiinflammatorydrugsandinflammatoryboweldisease AT ramieliakim nonsteroidalantiinflammatorydrugsandinflammatoryboweldisease |