Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease

Inflammatory Bowel Diseases (IBD) are an immune mediated chronic or relapsing disorders of the gastrointestinal (GI) tract. IBD is characterized by a chronic intestinal inflammatory process with various components contributing to the pathogenesis of the disease including environmental factors such a...

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Main Authors: Amir Klein, Rami Eliakim
Format: Article
Language:English
Published: MDPI AG 2010-04-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/3/4/1084/
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author Amir Klein
Rami Eliakim
author_facet Amir Klein
Rami Eliakim
author_sort Amir Klein
collection DOAJ
description Inflammatory Bowel Diseases (IBD) are an immune mediated chronic or relapsing disorders of the gastrointestinal (GI) tract. IBD is characterized by a chronic intestinal inflammatory process with various components contributing to the pathogenesis of the disease including environmental factors such as smoking or use of Non Steroidal Anti-Inflammatory Drugs (NSAIDS). NSAIDS are among the most commonly used medications for the treatment of various inflammatory conditions. The main factor limiting NSAIDS use is the concern for the development of gastrointestinal toxicity including mucosal injury. A possible association between the use of NSAIDS and the onset or relapse of IBD has been repeatedly suggested. This article will review the current concepts and evidence of the relationship between IBD and NSAIDS.
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spelling doaj.art-68dea862441d4309b600a099c0f8b8d82022-12-21T20:59:48ZengMDPI AGPharmaceuticals1424-82472010-04-01341084109210.3390/ph3041084Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel DiseaseAmir KleinRami EliakimInflammatory Bowel Diseases (IBD) are an immune mediated chronic or relapsing disorders of the gastrointestinal (GI) tract. IBD is characterized by a chronic intestinal inflammatory process with various components contributing to the pathogenesis of the disease including environmental factors such as smoking or use of Non Steroidal Anti-Inflammatory Drugs (NSAIDS). NSAIDS are among the most commonly used medications for the treatment of various inflammatory conditions. The main factor limiting NSAIDS use is the concern for the development of gastrointestinal toxicity including mucosal injury. A possible association between the use of NSAIDS and the onset or relapse of IBD has been repeatedly suggested. This article will review the current concepts and evidence of the relationship between IBD and NSAIDS.http://www.mdpi.com/1424-8247/3/4/1084/NSAIDsIBDCrohn'sUlcerative Colitis
spellingShingle Amir Klein
Rami Eliakim
Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease
Pharmaceuticals
NSAIDs
IBD
Crohn's
Ulcerative Colitis
title Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease
title_full Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease
title_fullStr Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease
title_full_unstemmed Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease
title_short Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease
title_sort non steroidal anti inflammatory drugs and inflammatory bowel disease
topic NSAIDs
IBD
Crohn's
Ulcerative Colitis
url http://www.mdpi.com/1424-8247/3/4/1084/
work_keys_str_mv AT amirklein nonsteroidalantiinflammatorydrugsandinflammatoryboweldisease
AT ramieliakim nonsteroidalantiinflammatorydrugsandinflammatoryboweldisease