Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers

Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers

Abstract Background Gingivobuccal complex oral squamous cell carcinoma (GBC-OSCC) is an aggressive malignancy with high mortality often preceded by premalignant lesions, including leukoplakia. Previous studies have reported genomic drivers in OSCC, but much remains to be elucidated about DNA methyla...

Full description

Bibliographic Details
Main Authors: Mayuri Inchanalkar, Sumana Srivatsa, Srikant Ambatipudi, Priyanka G. Bhosale, Asawari Patil, Alejandro A. Schäffer, Niko Beerenwinkel, Manoj B. Mahimkar
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Clinical Epigenetics
Subjects:
Leukoplakia
Gingivobuccal complex cancers
OSCC
DNA methylation
Integrative analysis
Prognosis
Online Access:https://doi.org/10.1186/s13148-023-01510-z

Internet

https://doi.org/10.1186/s13148-023-01510-z

Similar Items