Anti-inflammation effects of the total saponin fraction from Dioscorea nipponica Makino on rats with gouty arthritis by influencing MAPK signalling pathway

Anti-inflammation effects of the total saponin fraction from Dioscorea nipponica Makino on rats with gouty arthritis by influencing MAPK signalling pathway

Abstract Background Dioscorea nipponica Makino is widely used in traditional Chinese medicine to treat gouty arthritis. Methods Sixty male Wistar rats were divided into six groups: the normal group, model group, colchicine group (COL) and three total saponin groups (RDN) (high dose [160 mg/kg], midd...

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Bibliographic Details
Main Authors: Qi Zhou, Hui Juan Sun, Shu Min Liu, Xi Hong Jiang, Qiu Yue Wang, Shuang Zhang, Dong Hua Yu
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Dioscorea nipponica Makino
Gouty arthritis (GA)
Mitogen-activated protein kinase (MAPK)
Peroxisome proliferators-activated receptors (PPARs)
Online Access:http://link.springer.com/article/10.1186/s12906-020-03055-7

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