Evidence mapping of traditional Chinese medicine in diabetic peripheral neuropathy treatment
Objective: Diabetic peripheral neuropathy (DPN) stands as a crucial complication of diabetes, significantly affecting patients’ quality of life. This study aims to elucidate the evidence distribution from clinical randomized controlled trials (RCTs) on DPN treatment with traditional Chinese medicine...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2024.1325607/full |
| _version_ | 1797238539336810496 |
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| author | Yujie Fu Yiming Wang Zhenghong Li Ke Huang Yating Gao Shanqiong Xu Qingna Li Xingfang Liu Guangde Zhang |
| author_facet | Yujie Fu Yiming Wang Zhenghong Li Ke Huang Yating Gao Shanqiong Xu Qingna Li Xingfang Liu Guangde Zhang |
| author_sort | Yujie Fu |
| collection | DOAJ |
| description | Objective: Diabetic peripheral neuropathy (DPN) stands as a crucial complication of diabetes, significantly affecting patients’ quality of life. This study aims to elucidate the evidence distribution from clinical randomized controlled trials (RCTs) on DPN treatment with traditional Chinese medicine (TCM) through evidence mapping.Methods: A comprehensive search was conducted from January 2017 to October 2022 in databases such as Wanfang (China Online Journals), CNKI (China National Knowledge Infrastructure), VIP (China Science and Technology Journal Database), SinoMed (Chinese Biomedical Literature Database), PubMed, Web of Science, and Cochrane Library. Literature related to the treatment of DPN with TCM was selected. From the 1,229 RCTs identified over the past 6 years, relevant data were extracted. The evidence mapping approach was utilized, and trends in publications, study scales, intervention types, and evaluation indicators were analyzed using descriptive text combined with tables and bubble charts.Results: Research on the treatment of DPN with TCM is extensive. The publication trend remains relatively stable with predominantly smaller sample sizes. The main treatments encompass oral Chinese medicine and traditional external treatments. The most common evaluation indicators are neurophysiological, efficiency rate, symptom signs, neuropathy scores, and traditional Chinese symptoms, with less focus on psychological status and the ankle-brachial index (ABI).Conclusion: Shedding light on contemporary research, this study explores the current RCTs evaluating TCM’s efficacy in treating DPN. The findings not only highlight the potential role of TCM in addressing diabetic complications but also underscore areas that could benefit from refined research approaches, expanded intervention methods, and broader assessment criteria. Our observations aim to inform and inspire future research directions and clinical practices concerning TCM’s role in managing diabetes-associated complications. |
| first_indexed | 2024-04-24T17:37:15Z |
| format | Article |
| id | doaj.art-68e914ee8437407bbc1fdbcfee6213ff |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-24T17:37:15Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-68e914ee8437407bbc1fdbcfee6213ff2024-03-28T04:34:15ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122024-03-011510.3389/fphar.2024.13256071325607Evidence mapping of traditional Chinese medicine in diabetic peripheral neuropathy treatmentYujie Fu0Yiming Wang1Zhenghong Li2Ke Huang3Yating Gao4Shanqiong Xu5Qingna Li6Xingfang Liu7Guangde Zhang8Graduate School, Beijing University of Chinese Medicine, Beijing, ChinaGraduate School, China Academy of Chinese Medical Sciences, Beijing, ChinaResearch Department, Swiss University of Traditional Chinese Medicine, Bad Zurzach, SwitzerlandInstitute of Endocrinology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaGraduate School, Beijing University of Chinese Medicine, Beijing, ChinaGraduate School, Beijing University of Chinese Medicine, Beijing, ChinaInstitute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaResearch Department, Swiss University of Traditional Chinese Medicine, Bad Zurzach, SwitzerlandInstitute of Endocrinology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaObjective: Diabetic peripheral neuropathy (DPN) stands as a crucial complication of diabetes, significantly affecting patients’ quality of life. This study aims to elucidate the evidence distribution from clinical randomized controlled trials (RCTs) on DPN treatment with traditional Chinese medicine (TCM) through evidence mapping.Methods: A comprehensive search was conducted from January 2017 to October 2022 in databases such as Wanfang (China Online Journals), CNKI (China National Knowledge Infrastructure), VIP (China Science and Technology Journal Database), SinoMed (Chinese Biomedical Literature Database), PubMed, Web of Science, and Cochrane Library. Literature related to the treatment of DPN with TCM was selected. From the 1,229 RCTs identified over the past 6 years, relevant data were extracted. The evidence mapping approach was utilized, and trends in publications, study scales, intervention types, and evaluation indicators were analyzed using descriptive text combined with tables and bubble charts.Results: Research on the treatment of DPN with TCM is extensive. The publication trend remains relatively stable with predominantly smaller sample sizes. The main treatments encompass oral Chinese medicine and traditional external treatments. The most common evaluation indicators are neurophysiological, efficiency rate, symptom signs, neuropathy scores, and traditional Chinese symptoms, with less focus on psychological status and the ankle-brachial index (ABI).Conclusion: Shedding light on contemporary research, this study explores the current RCTs evaluating TCM’s efficacy in treating DPN. The findings not only highlight the potential role of TCM in addressing diabetic complications but also underscore areas that could benefit from refined research approaches, expanded intervention methods, and broader assessment criteria. Our observations aim to inform and inspire future research directions and clinical practices concerning TCM’s role in managing diabetes-associated complications.https://www.frontiersin.org/articles/10.3389/fphar.2024.1325607/fulldiabetic peripheral neuropathydiabetescomplicationstraditional Chinese medicinerandomized controlled trialsystematic review |
| spellingShingle | Yujie Fu Yiming Wang Zhenghong Li Ke Huang Yating Gao Shanqiong Xu Qingna Li Xingfang Liu Guangde Zhang Evidence mapping of traditional Chinese medicine in diabetic peripheral neuropathy treatment Frontiers in Pharmacology diabetic peripheral neuropathy diabetes complications traditional Chinese medicine randomized controlled trial systematic review |
| title | Evidence mapping of traditional Chinese medicine in diabetic peripheral neuropathy treatment |
| title_full | Evidence mapping of traditional Chinese medicine in diabetic peripheral neuropathy treatment |
| title_fullStr | Evidence mapping of traditional Chinese medicine in diabetic peripheral neuropathy treatment |
| title_full_unstemmed | Evidence mapping of traditional Chinese medicine in diabetic peripheral neuropathy treatment |
| title_short | Evidence mapping of traditional Chinese medicine in diabetic peripheral neuropathy treatment |
| title_sort | evidence mapping of traditional chinese medicine in diabetic peripheral neuropathy treatment |
| topic | diabetic peripheral neuropathy diabetes complications traditional Chinese medicine randomized controlled trial systematic review |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2024.1325607/full |
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