Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients
OBJECTIVE: To evaluate the pattern of serum electrolytes abnormalities and their impact on ICU admitted Covid-19 patient outcomes. METHODOLOGY: This retrospective study was carried out at OMI hospital and Dr. Ziauddin Hospital, Karachi, Pakistan, between August to December 2020. Total 102 PCR po...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Liaquat University of Medical and Health Sciences
2022-03-01
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| Series: | JLUMHS |
| Subjects: | |
| Online Access: | https://www.lumhs.edu.pk/jlumhs/Vol21No01/04.pdf |
| Summary: | OBJECTIVE: To evaluate the pattern of serum electrolytes abnormalities and their impact on ICU admitted Covid-19 patient outcomes.
METHODOLOGY: This retrospective study was carried out at OMI hospital and Dr. Ziauddin Hospital, Karachi, Pakistan, between August to December 2020. Total 102 PCR positive, ICU admitted with severe Covid-19 patients as per WHO criteria were included. The patient's demographic characteristics, clinical features including co-morbidities, electrolytes reports at the time of admission, length of ICU and/or hospital stay, and outcome (expired/survived) were evaluated.
RESULTS: Biochemical testing found abnormal electrolyte levels in 90.2% ICU admitted Covid-19 patients. Electrolytes abnormalities including hyponatremia 45.1%, hypermagnesemia 40.2%, hypocalcemia 31.4%, hyperchloremia23.5% and hyperphosphatemia in 20.6% patients. Out of the total, 28.4% of patients needed invasive respiratory support, and 37.3% could not survive. A higher incidence of mortality (39.1% vs. 20%) was seen in patients with electrolytes abnormalities compared to those presented with normal values. CONCLUSION: Electrolyte abnormalities were found in 90% of the ICU Admitted Covid-19 patients. The most common abnormalities found among the patients were hyponatremia, hypermagnesemia, and Hypocalcemia. The findings revealed that several electrolyte imbalances harm patients' in-hospital outcomes. Electrolyte assessment of Covid-19 patients at the time of admission would be helpful in risk stratification for adverse outcomes.
BSTRACT
OBJECTIVE: To evaluate the pattern of serum electrolytes abnormalities and their impact on ICU
admitted Covid-19 patient outcomes.
METHODOLOGY: This retrospective study was carried out at OMI hospital and Dr. Ziauddin Hospital,
Karachi, Pakistan, between August to December 2020. Total 102 PCR positive, ICU admitted with severe
Covid-19 patients as per WHO criteria were included. The patient's demographic characteristics, clinical
features including co-morbidities, electrolytes reports at the time of admission, length of ICU and/or
hospital stay, and outcome (expired/survived) were evaluated.
RESULTS: Biochemical testing found abnormal electrolyte levels in 90.2% ICU admitted Covid-19
patients. Electrolytes abnormalities including hyponatremia 45.1%, hypermagnesemia 40.2%,
hypocalcemia 31.4%, hyperchloremia23.5% and hyperphosphatemia in 20.6% patients. Out of the total,
28.4% of patients needed invasive respiratory support, and 37.3% could not survive. A higher incidence
of mortality (39.1% vs. 20%) was seen in patients with electrolytes abnormalities compared to those
presented with normal values.
CONCLUSION: Electrolyte abnormalities were found in 90% of the ICU Admitted Covid-19 patients. The
most common abnormalities found among the patients were hyponatremia, hypermagnesemia, and
Hypocalcemia. The findings revealed that several electrolyte imbalances harm patients' in-hospital outcomes. Electrolyte assessment of Covid-19 patients at the time of admission would be helpful in risk
stratification for adverse outcomes. |
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| ISSN: | 1729-0341 2309-8627 |