Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients
OBJECTIVE: To evaluate the pattern of serum electrolytes abnormalities and their impact on ICU admitted Covid-19 patient outcomes. METHODOLOGY: This retrospective study was carried out at OMI hospital and Dr. Ziauddin Hospital, Karachi, Pakistan, between August to December 2020. Total 102 PCR po...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Liaquat University of Medical and Health Sciences
2022-03-01
|
| Series: | JLUMHS |
| Subjects: | |
| Online Access: | https://www.lumhs.edu.pk/jlumhs/Vol21No01/04.pdf |
| _version_ | 1797826772261142528 |
|---|---|
| author | Anita Haroon Syed Ali Abbas Amanullah Khan Momina Ali Rija Qazi Ajeet Kumar |
| author_facet | Anita Haroon Syed Ali Abbas Amanullah Khan Momina Ali Rija Qazi Ajeet Kumar |
| author_sort | Anita Haroon |
| collection | DOAJ |
| description | OBJECTIVE: To evaluate the pattern of serum electrolytes abnormalities and their impact on ICU admitted Covid-19 patient outcomes.
METHODOLOGY: This retrospective study was carried out at OMI hospital and Dr. Ziauddin Hospital, Karachi, Pakistan, between August to December 2020. Total 102 PCR positive, ICU admitted with severe Covid-19 patients as per WHO criteria were included. The patient's demographic characteristics, clinical features including co-morbidities, electrolytes reports at the time of admission, length of ICU and/or hospital stay, and outcome (expired/survived) were evaluated.
RESULTS: Biochemical testing found abnormal electrolyte levels in 90.2% ICU admitted Covid-19 patients. Electrolytes abnormalities including hyponatremia 45.1%, hypermagnesemia 40.2%, hypocalcemia 31.4%, hyperchloremia23.5% and hyperphosphatemia in 20.6% patients. Out of the total, 28.4% of patients needed invasive respiratory support, and 37.3% could not survive. A higher incidence of mortality (39.1% vs. 20%) was seen in patients with electrolytes abnormalities compared to those presented with normal values. CONCLUSION: Electrolyte abnormalities were found in 90% of the ICU Admitted Covid-19 patients. The most common abnormalities found among the patients were hyponatremia, hypermagnesemia, and Hypocalcemia. The findings revealed that several electrolyte imbalances harm patients' in-hospital outcomes. Electrolyte assessment of Covid-19 patients at the time of admission would be helpful in risk stratification for adverse outcomes.
BSTRACT
OBJECTIVE: To evaluate the pattern of serum electrolytes abnormalities and their impact on ICU
admitted Covid-19 patient outcomes.
METHODOLOGY: This retrospective study was carried out at OMI hospital and Dr. Ziauddin Hospital,
Karachi, Pakistan, between August to December 2020. Total 102 PCR positive, ICU admitted with severe
Covid-19 patients as per WHO criteria were included. The patient's demographic characteristics, clinical
features including co-morbidities, electrolytes reports at the time of admission, length of ICU and/or
hospital stay, and outcome (expired/survived) were evaluated.
RESULTS: Biochemical testing found abnormal electrolyte levels in 90.2% ICU admitted Covid-19
patients. Electrolytes abnormalities including hyponatremia 45.1%, hypermagnesemia 40.2%,
hypocalcemia 31.4%, hyperchloremia23.5% and hyperphosphatemia in 20.6% patients. Out of the total,
28.4% of patients needed invasive respiratory support, and 37.3% could not survive. A higher incidence
of mortality (39.1% vs. 20%) was seen in patients with electrolytes abnormalities compared to those
presented with normal values.
CONCLUSION: Electrolyte abnormalities were found in 90% of the ICU Admitted Covid-19 patients. The
most common abnormalities found among the patients were hyponatremia, hypermagnesemia, and
Hypocalcemia. The findings revealed that several electrolyte imbalances harm patients' in-hospital outcomes. Electrolyte assessment of Covid-19 patients at the time of admission would be helpful in risk
stratification for adverse outcomes. |
| first_indexed | 2024-04-09T12:37:35Z |
| format | Article |
| id | doaj.art-68ed3cba900b4d19844fe9bc1a8763eb |
| institution | Directory Open Access Journal |
| issn | 1729-0341 2309-8627 |
| language | English |
| last_indexed | 2024-04-09T12:37:35Z |
| publishDate | 2022-03-01 |
| publisher | Liaquat University of Medical and Health Sciences |
| record_format | Article |
| series | JLUMHS |
| spelling | doaj.art-68ed3cba900b4d19844fe9bc1a8763eb2023-05-15T06:37:33ZengLiaquat University of Medical and Health SciencesJLUMHS1729-03412309-86272022-03-0121011622doi:10.22442/jlumhs.2022.00905Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 PatientsAnita Haroon0Syed Ali Abbas1 Amanullah Khan2Momina Ali3Rija Qazi4Ajeet Kumar5Baqai Medical University OMI Hospital Karachi, Sindh-PakistanBaqai Medical University OMI Hospital Karachi, Sindh-PakistanBaqai Medical University OMI Hospital Karachi, Sindh-PakistanDr. Ziauddin University Hospital Karachi, Sindh-PakistaDr. Ziauddin University Hospital Karachi, Sindh-PakistaJinnah Medical College Hospital Karachi, Sindh-Pakistan. OBJECTIVE: To evaluate the pattern of serum electrolytes abnormalities and their impact on ICU admitted Covid-19 patient outcomes. METHODOLOGY: This retrospective study was carried out at OMI hospital and Dr. Ziauddin Hospital, Karachi, Pakistan, between August to December 2020. Total 102 PCR positive, ICU admitted with severe Covid-19 patients as per WHO criteria were included. The patient's demographic characteristics, clinical features including co-morbidities, electrolytes reports at the time of admission, length of ICU and/or hospital stay, and outcome (expired/survived) were evaluated. RESULTS: Biochemical testing found abnormal electrolyte levels in 90.2% ICU admitted Covid-19 patients. Electrolytes abnormalities including hyponatremia 45.1%, hypermagnesemia 40.2%, hypocalcemia 31.4%, hyperchloremia23.5% and hyperphosphatemia in 20.6% patients. Out of the total, 28.4% of patients needed invasive respiratory support, and 37.3% could not survive. A higher incidence of mortality (39.1% vs. 20%) was seen in patients with electrolytes abnormalities compared to those presented with normal values. CONCLUSION: Electrolyte abnormalities were found in 90% of the ICU Admitted Covid-19 patients. The most common abnormalities found among the patients were hyponatremia, hypermagnesemia, and Hypocalcemia. The findings revealed that several electrolyte imbalances harm patients' in-hospital outcomes. Electrolyte assessment of Covid-19 patients at the time of admission would be helpful in risk stratification for adverse outcomes. BSTRACT OBJECTIVE: To evaluate the pattern of serum electrolytes abnormalities and their impact on ICU admitted Covid-19 patient outcomes. METHODOLOGY: This retrospective study was carried out at OMI hospital and Dr. Ziauddin Hospital, Karachi, Pakistan, between August to December 2020. Total 102 PCR positive, ICU admitted with severe Covid-19 patients as per WHO criteria were included. The patient's demographic characteristics, clinical features including co-morbidities, electrolytes reports at the time of admission, length of ICU and/or hospital stay, and outcome (expired/survived) were evaluated. RESULTS: Biochemical testing found abnormal electrolyte levels in 90.2% ICU admitted Covid-19 patients. Electrolytes abnormalities including hyponatremia 45.1%, hypermagnesemia 40.2%, hypocalcemia 31.4%, hyperchloremia23.5% and hyperphosphatemia in 20.6% patients. Out of the total, 28.4% of patients needed invasive respiratory support, and 37.3% could not survive. A higher incidence of mortality (39.1% vs. 20%) was seen in patients with electrolytes abnormalities compared to those presented with normal values. CONCLUSION: Electrolyte abnormalities were found in 90% of the ICU Admitted Covid-19 patients. The most common abnormalities found among the patients were hyponatremia, hypermagnesemia, and Hypocalcemia. The findings revealed that several electrolyte imbalances harm patients' in-hospital outcomes. Electrolyte assessment of Covid-19 patients at the time of admission would be helpful in risk stratification for adverse outcomes.https://www.lumhs.edu.pk/jlumhs/Vol21No01/04.pdfcovid-19critically illicu stayserum electrolytesabnormalitiesrespiratory support |
| spellingShingle | Anita Haroon Syed Ali Abbas Amanullah Khan Momina Ali Rija Qazi Ajeet Kumar Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients JLUMHS covid-19 critically ill icu stay serum electrolytes abnormalities respiratory support |
| title | Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients |
| title_full | Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients |
| title_fullStr | Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients |
| title_full_unstemmed | Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients |
| title_short | Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients |
| title_sort | evaluation of pattern and impact of electrolytes abnormalities in critically ill covid 19 patients |
| topic | covid-19 critically ill icu stay serum electrolytes abnormalities respiratory support |
| url | https://www.lumhs.edu.pk/jlumhs/Vol21No01/04.pdf |
| work_keys_str_mv | AT anitaharoon evaluationofpatternandimpactofelectrolytesabnormalitiesincriticallyillcovid19patients AT syedaliabbas evaluationofpatternandimpactofelectrolytesabnormalitiesincriticallyillcovid19patients AT amanullahkhan evaluationofpatternandimpactofelectrolytesabnormalitiesincriticallyillcovid19patients AT mominaali evaluationofpatternandimpactofelectrolytesabnormalitiesincriticallyillcovid19patients AT rijaqazi evaluationofpatternandimpactofelectrolytesabnormalitiesincriticallyillcovid19patients AT ajeetkumar evaluationofpatternandimpactofelectrolytesabnormalitiesincriticallyillcovid19patients |