Transcriptome Profiling Identifies Multiplexin as a Target of SAGA Deubiquitinase Activity in Glia Required for Precise Axon Guidance During Drosophila Visual Development

Transcriptome Profiling Identifies Multiplexin as a Target of SAGA Deubiquitinase Activity in Glia Required for Precise Axon Guidance During Drosophila Visual Development

The Spt-Ada-Gcn5 Acetyltransferase (SAGA) complex is a transcriptional coactivator with histone acetylase and deubiquitinase activities that plays an important role in visual development and function. In Drosophila melanogaster, four SAGA subunits are required for the deubiquitination of monoubiquit...

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Bibliographic Details
Main Authors: Jingqun Ma, Kaelan J. Brennan, Mitch R. D’Aloia, Pete E. Pascuzzi, Vikki M. Weake
Format: Article
Language:English
Published: Oxford University Press 2016-08-01
Series:G3: Genes, Genomes, Genetics
Subjects:
histone ubiquitination
glia
axon guidance
SAGA
SCA7
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.031310

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