Spirometry use in patients with sickle cell disease with and without asthma and acute chest syndrome: A multicenter study
Abstract A de‐identified data repository of electronic medical record data, i2b2 (Informatics for Integrating Biology and the Bedside), including four geographically diverse academic medical centers, was queried to determine the use of diagnostic spirometry testing in African American children and y...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-07-01
|
| Series: | eJHaem |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jha2.42 |
| _version_ | 1797739963373060096 |
|---|---|
| author | Laurie Duckworth Lucien Vandy Black Dima Ezmigna Jeanette Green Yingwei Yao Shaun Grannis Jeff Klann Reuben Applegate Gigi Lipori Tanya Wallace Diana J. Wilkie |
| author_facet | Laurie Duckworth Lucien Vandy Black Dima Ezmigna Jeanette Green Yingwei Yao Shaun Grannis Jeff Klann Reuben Applegate Gigi Lipori Tanya Wallace Diana J. Wilkie |
| author_sort | Laurie Duckworth |
| collection | DOAJ |
| description | Abstract A de‐identified data repository of electronic medical record data, i2b2 (Informatics for Integrating Biology and the Bedside), including four geographically diverse academic medical centers, was queried to determine the use of diagnostic spirometry testing in African American children and young adults 5‐34 years of age with sickle cell disease (SCD) with or without a documented history of asthma and/or acute chest syndrome (ACS). A total of 2749 patients were identified with SCD, of these 577 had asthma and 409 had ACS. Cross‐referencing the CPT code for diagnostic spirometry showed that for patients identified as having SCD, a history of ACS, and a diagnosis of asthma, only 31% across all four centers had spirometry. Having an asthma diagnosis was associated with ACS. Among SCD patients with asthma, the proportion with ACS for the four centers was 47%, 75%, 38%, and 36% respectively. The bivariate association between asthma and ACS for each Center was significant for each (P < .001). To summarize, only one third of patients with co‐morbid SCD, ACS, and asthma received the spirometry procedure as recommended in evidence‐based guidelines, suggesting limited testing for changes in pulmonary function. Future studies to determine barriers and facilitators to implementation of pulmonary testing in SCD are warranted. |
| first_indexed | 2024-03-12T14:05:44Z |
| format | Article |
| id | doaj.art-68fb84a57c2a4015aa41e4149e20ea6e |
| institution | Directory Open Access Journal |
| issn | 2688-6146 |
| language | English |
| last_indexed | 2024-03-12T14:05:44Z |
| publishDate | 2020-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | eJHaem |
| spelling | doaj.art-68fb84a57c2a4015aa41e4149e20ea6e2023-08-21T14:10:49ZengWileyeJHaem2688-61462020-07-011123924210.1002/jha2.42Spirometry use in patients with sickle cell disease with and without asthma and acute chest syndrome: A multicenter studyLaurie Duckworth0Lucien Vandy Black1Dima Ezmigna2Jeanette Green3Yingwei Yao4Shaun Grannis5Jeff Klann6Reuben Applegate7Gigi Lipori8Tanya Wallace9Diana J. Wilkie10College of Nursing UF Health University of Florida Gainesville FLDivision of Pediatric Hematology and Oncology University of Florida College of MedicineDivision of Pulmonology UF HealthBiobehavioral Nursing Science AdventHealthBiobehavioral Nursing Science University of Florida College of NursingIndiana University School of MedicineHarvard Medicine Massachusetts General HospitalUniversity of Texas Health Science Center at Houston, ResearchUF Health Shands VP Information ServicesCollege of Nursing University of FloridaBiobehavioral Nursing Science University of Florida College of NursingAbstract A de‐identified data repository of electronic medical record data, i2b2 (Informatics for Integrating Biology and the Bedside), including four geographically diverse academic medical centers, was queried to determine the use of diagnostic spirometry testing in African American children and young adults 5‐34 years of age with sickle cell disease (SCD) with or without a documented history of asthma and/or acute chest syndrome (ACS). A total of 2749 patients were identified with SCD, of these 577 had asthma and 409 had ACS. Cross‐referencing the CPT code for diagnostic spirometry showed that for patients identified as having SCD, a history of ACS, and a diagnosis of asthma, only 31% across all four centers had spirometry. Having an asthma diagnosis was associated with ACS. Among SCD patients with asthma, the proportion with ACS for the four centers was 47%, 75%, 38%, and 36% respectively. The bivariate association between asthma and ACS for each Center was significant for each (P < .001). To summarize, only one third of patients with co‐morbid SCD, ACS, and asthma received the spirometry procedure as recommended in evidence‐based guidelines, suggesting limited testing for changes in pulmonary function. Future studies to determine barriers and facilitators to implementation of pulmonary testing in SCD are warranted.https://doi.org/10.1002/jha2.42asthmapediatric hematologysickle cell disease |
| spellingShingle | Laurie Duckworth Lucien Vandy Black Dima Ezmigna Jeanette Green Yingwei Yao Shaun Grannis Jeff Klann Reuben Applegate Gigi Lipori Tanya Wallace Diana J. Wilkie Spirometry use in patients with sickle cell disease with and without asthma and acute chest syndrome: A multicenter study eJHaem asthma pediatric hematology sickle cell disease |
| title | Spirometry use in patients with sickle cell disease with and without asthma and acute chest syndrome: A multicenter study |
| title_full | Spirometry use in patients with sickle cell disease with and without asthma and acute chest syndrome: A multicenter study |
| title_fullStr | Spirometry use in patients with sickle cell disease with and without asthma and acute chest syndrome: A multicenter study |
| title_full_unstemmed | Spirometry use in patients with sickle cell disease with and without asthma and acute chest syndrome: A multicenter study |
| title_short | Spirometry use in patients with sickle cell disease with and without asthma and acute chest syndrome: A multicenter study |
| title_sort | spirometry use in patients with sickle cell disease with and without asthma and acute chest syndrome a multicenter study |
| topic | asthma pediatric hematology sickle cell disease |
| url | https://doi.org/10.1002/jha2.42 |
| work_keys_str_mv | AT laurieduckworth spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT lucienvandyblack spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT dimaezmigna spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT jeanettegreen spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT yingweiyao spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT shaungrannis spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT jeffklann spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT reubenapplegate spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT gigilipori spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT tanyawallace spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy AT dianajwilkie spirometryuseinpatientswithsicklecelldiseasewithandwithoutasthmaandacutechestsyndromeamulticenterstudy |