Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis

Syphilis is a rare cause of panuveitis. We present the case of a 33-year-old man who presented with diminution of vision of three months duration in his left eye (OS), without any other systemic illness. Ophthalmic examination showed features of pauveitis with dense vitreous exudates, disc pallor an...

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Main Authors: Jay Kumar Chhablani, J Biswas, S Sudharshan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2010-01-01
Series:Oman Journal of Ophthalmology
Subjects:
Online Access:http://www.ojoonline.org/article.asp?issn=0974-620X;year=2010;volume=3;issue=1;spage=29;epage=31;aulast=Chhablani
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author Jay Kumar Chhablani
J Biswas
S Sudharshan
author_facet Jay Kumar Chhablani
J Biswas
S Sudharshan
author_sort Jay Kumar Chhablani
collection DOAJ
description Syphilis is a rare cause of panuveitis. We present the case of a 33-year-old man who presented with diminution of vision of three months duration in his left eye (OS), without any other systemic illness. Ophthalmic examination showed features of pauveitis with dense vitreous exudates, disc pallor and sheathing of vessels on fundoscopy. A diagnosis of probable endogenous endophthalmitis was made and vitreous tap performed. Vitreous biopsy showed no growth of fungus or bacteria. Rapid plasma reagin (RPR) and Treponema pallidum hemagglutination (TPHA) test were positive. Enzyme-Linked Immuno Sorbent Assay (ELISA) and Western Blot test were then performed, which revealed concurrent HIV infection. The patient improved dramatically with intravenous penicillin therapy. HIV positive patients may present with panuveitis secondary to ocular syphilis, as the only presenting feature in HIV positive patient in absence of any other systemic features.
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spelling doaj.art-68fd99c4c3884fcda117a06d0d5474672022-12-22T03:06:45ZengWolters Kluwer Medknow PublicationsOman Journal of Ophthalmology0974-620X2010-01-0131293110.4103/0974-620X.60019Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosisJay Kumar ChhablaniJ BiswasS SudharshanSyphilis is a rare cause of panuveitis. We present the case of a 33-year-old man who presented with diminution of vision of three months duration in his left eye (OS), without any other systemic illness. Ophthalmic examination showed features of pauveitis with dense vitreous exudates, disc pallor and sheathing of vessels on fundoscopy. A diagnosis of probable endogenous endophthalmitis was made and vitreous tap performed. Vitreous biopsy showed no growth of fungus or bacteria. Rapid plasma reagin (RPR) and Treponema pallidum hemagglutination (TPHA) test were positive. Enzyme-Linked Immuno Sorbent Assay (ELISA) and Western Blot test were then performed, which revealed concurrent HIV infection. The patient improved dramatically with intravenous penicillin therapy. HIV positive patients may present with panuveitis secondary to ocular syphilis, as the only presenting feature in HIV positive patient in absence of any other systemic features.http://www.ojoonline.org/article.asp?issn=0974-620X;year=2010;volume=3;issue=1;spage=29;epage=31;aulast=ChhablaniHIVocular syphilis in HIVsyphilitic panuveitis in HIV
spellingShingle Jay Kumar Chhablani
J Biswas
S Sudharshan
Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis
Oman Journal of Ophthalmology
HIV
ocular syphilis in HIV
syphilitic panuveitis in HIV
title Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis
title_full Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis
title_fullStr Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis
title_full_unstemmed Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis
title_short Panuveitis as a manifestation of ocular syphilis leading to HIV diagnosis
title_sort panuveitis as a manifestation of ocular syphilis leading to hiv diagnosis
topic HIV
ocular syphilis in HIV
syphilitic panuveitis in HIV
url http://www.ojoonline.org/article.asp?issn=0974-620X;year=2010;volume=3;issue=1;spage=29;epage=31;aulast=Chhablani
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