SRSF2 mutation reduces polycythemia and impairs hematopoietic progenitor functions in JAK2V617F-driven myeloproliferative neoplasm

SRSF2 mutation reduces polycythemia and impairs hematopoietic progenitor functions in JAK2V617F-driven myeloproliferative neoplasm

Abstract SRSF2 mutations are found in association with JAK2V617F in myeloproliferative neoplasms (MPN), most frequently in myelofibrosis (MF). However, the contribution of SRSF2 mutation in JAK2V617F-driven MPN remains elusive. To investigate the consequences of SRSF2P95H and JAK2V617F mutations in...

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Bibliographic Details
Main Authors: Yue Yang, Salar Abbas, Mohammad A. Sayem, Avik Dutta, Golam Mohi
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-023-00947-y

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