Copper Toxicity Is Not Just Oxidative Damage: Zinc Systems and Insight from Wilson Disease

Copper Toxicity Is Not Just Oxidative Damage: Zinc Systems and Insight from Wilson Disease

Essential metals such as copper (Cu) and zinc (Zn) are important cofactors in diverse cellular processes, while metal imbalance may impact or be altered by disease state. Cu is essential for aerobic life with significant functions in oxidation-reduction catalysis. This redox reactivity requires prec...

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Bibliographic Details
Main Authors: R. G. Barber, Zoey A. Grenier, Jason L. Burkhead
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomedicines
Subjects:
copper
zinc
Wilson Disease
copper toxicity
oxidative stress
Online Access:https://www.mdpi.com/2227-9059/9/3/316

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