Role of Antibiotic Cement Coated Nailing in Infected Nonunion of Tibia

INTRODUCTION: Infected nonunion of long bones is a chronic and debilitating disorder. It is more difficult to deal with when the implant used for internal fixation itself becomes a potential media for infection because of bacterial adhesion and biofilm formation. Traditionally, it is managed by two-...

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Main Authors: Bhatia C, Tiwari AK, Sharma SB, Thalanki S, Rai A
Format: Article
Language:English
Published: Malaysian Orthopaedic Association 2017-03-01
Series:Malaysian Orthopaedic Journal
Subjects:
Online Access:http://www.morthoj.org/2017/v11n1/antibiotic-cement-coated-nailing.pdf
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author Bhatia C
Tiwari AK
Sharma SB
Thalanki S
Rai A
author_facet Bhatia C
Tiwari AK
Sharma SB
Thalanki S
Rai A
author_sort Bhatia C
collection DOAJ
description INTRODUCTION: Infected nonunion of long bones is a chronic and debilitating disorder. It is more difficult to deal with when the implant used for internal fixation itself becomes a potential media for infection because of bacterial adhesion and biofilm formation. Traditionally, it is managed by two- stage procedure for controlling the infection first and then treating the nonunion. This study has been undertaken to explore antibiotic cement coated nailing as single stage treatment modality for treating infection and achieving stability at the same time. MATERIALS AND METHODS: Twenty patients (above 18 years age) with infected nonunion of tibia with bone gap less than 2 cm were managed using antibiotic cement coated K-nail. Antibiotic cement nail was prepared using endotracheal tube method. Antibiotics used were a combination of vancomycin and teicoplanin. RESULTS: Infection was controlled in 95% of the patients. Bony union was achieved in 12 of 20 (60%) patients with antibiotic cement nailing as the only procedure with average time of union of 32 weeks. Remaining 8 patients required additional procedures like bone grafting or exchange nailing and these were done in six patients, with union of fracture. Two patients refused to undergo further procedures. Complications encountered were difficult nail removal in three cases, broken nail in two cases, and bent nail in one case. Recurrence of infection was observed in two patients. Average period of follow-up was 13 months. CONCLUSION: Antibiotic cement impregnated nailing is a simple, economical and effective single stage procedure for the management of infected nonunion of tibia. It is advantageous over external fixators, as it eliminates the complications of external fixators and has good patient compliance. The method utilizes existing easily available instrumentation and materials and is technically less demanding, and therefore can be performed at any general orthopaedic center.
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spelling doaj.art-6908a9ecb3a949b08e196d08813a6aa62022-12-21T20:21:38ZengMalaysian Orthopaedic AssociationMalaysian Orthopaedic Journal1985-25332017-03-01111611http://dx.doi.org/10.5704/MOJ.1703.019Role of Antibiotic Cement Coated Nailing in Infected Nonunion of TibiaBhatia C0Tiwari AK1Sharma SB2Thalanki S3Rai A4MS OrthMS OrthMS OrthMS OrthMS OrthINTRODUCTION: Infected nonunion of long bones is a chronic and debilitating disorder. It is more difficult to deal with when the implant used for internal fixation itself becomes a potential media for infection because of bacterial adhesion and biofilm formation. Traditionally, it is managed by two- stage procedure for controlling the infection first and then treating the nonunion. This study has been undertaken to explore antibiotic cement coated nailing as single stage treatment modality for treating infection and achieving stability at the same time. MATERIALS AND METHODS: Twenty patients (above 18 years age) with infected nonunion of tibia with bone gap less than 2 cm were managed using antibiotic cement coated K-nail. Antibiotic cement nail was prepared using endotracheal tube method. Antibiotics used were a combination of vancomycin and teicoplanin. RESULTS: Infection was controlled in 95% of the patients. Bony union was achieved in 12 of 20 (60%) patients with antibiotic cement nailing as the only procedure with average time of union of 32 weeks. Remaining 8 patients required additional procedures like bone grafting or exchange nailing and these were done in six patients, with union of fracture. Two patients refused to undergo further procedures. Complications encountered were difficult nail removal in three cases, broken nail in two cases, and bent nail in one case. Recurrence of infection was observed in two patients. Average period of follow-up was 13 months. CONCLUSION: Antibiotic cement impregnated nailing is a simple, economical and effective single stage procedure for the management of infected nonunion of tibia. It is advantageous over external fixators, as it eliminates the complications of external fixators and has good patient compliance. The method utilizes existing easily available instrumentation and materials and is technically less demanding, and therefore can be performed at any general orthopaedic center.http://www.morthoj.org/2017/v11n1/antibiotic-cement-coated-nailing.pdfnonunioninfectedantibioticcementnailing
spellingShingle Bhatia C
Tiwari AK
Sharma SB
Thalanki S
Rai A
Role of Antibiotic Cement Coated Nailing in Infected Nonunion of Tibia
Malaysian Orthopaedic Journal
nonunion
infected
antibiotic
cement
nailing
title Role of Antibiotic Cement Coated Nailing in Infected Nonunion of Tibia
title_full Role of Antibiotic Cement Coated Nailing in Infected Nonunion of Tibia
title_fullStr Role of Antibiotic Cement Coated Nailing in Infected Nonunion of Tibia
title_full_unstemmed Role of Antibiotic Cement Coated Nailing in Infected Nonunion of Tibia
title_short Role of Antibiotic Cement Coated Nailing in Infected Nonunion of Tibia
title_sort role of antibiotic cement coated nailing in infected nonunion of tibia
topic nonunion
infected
antibiotic
cement
nailing
url http://www.morthoj.org/2017/v11n1/antibiotic-cement-coated-nailing.pdf
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AT thalankis roleofantibioticcementcoatednailingininfectednonunionoftibia
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