Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in Japan
Background: It is known that physical activity affects glucose metabolism. However, there have been no reports on the influence of physical activity earlier in life on subsequent glucose metabolism. Therefore, we analyzed the influence of physical activity in earlier decades of life on insulin resis...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Japan Epidemiological Association
2019-02-01
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| Series: | Journal of Epidemiology |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jea/29/2/29_JE20170180/_pdf |
| _version_ | 1828521770100981760 |
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| author | Hitomi Fujita Akihiro Hosono Kiyoshi Shibata Shoko Tsujimura Kyoko Oka Naoko Okamoto Mayumi Kamiya Fumi Kondo Ryozo Wakabayashi Mari Ichikawa Tamaki Yamada Sadao Suzuki |
| author_facet | Hitomi Fujita Akihiro Hosono Kiyoshi Shibata Shoko Tsujimura Kyoko Oka Naoko Okamoto Mayumi Kamiya Fumi Kondo Ryozo Wakabayashi Mari Ichikawa Tamaki Yamada Sadao Suzuki |
| author_sort | Hitomi Fujita |
| collection | DOAJ |
| description | Background: It is known that physical activity affects glucose metabolism. However, there have been no reports on the influence of physical activity earlier in life on subsequent glucose metabolism. Therefore, we analyzed the influence of physical activity in earlier decades of life on insulin resistance in middle aged and older residents in Japan. Methods: The subjects were 6,883 residents of Okazaki City between the ages of 40 and 79 years who underwent physical examinations at the Okazaki City Medical Association Public Health Center from April 2007 through August 2011. They gave informed consent for participation in the study. Data on individual characteristics were collected via a questionnaire and from the health examination records. Fasting blood glucose and insulin levels were used to calculate the homeostatic model assessment of insulin resistance (HOMA-IR). HOMA-IR >1.6 was considered to indicate insulin resistance for the purpose of logistic regression models. Results: The study sample included 3,683 men and 3,200 women for whom complete information was available. For those who exercised regularly throughout their teens to their 30s–40s, the odds ratio for having insulin resistance was 0.75 (95% confidence interval [CI], 0.58–0.96) for men and 0.76 (95% CI, 0.58–0.99) for women after adjusting for other variables, including age, body mass index, and present physical activity. A linear trend was also observed in both men and women. Conclusions: Subjects who have exercised regularly in the early decades of life are less likely to have insulin resistance later in life. |
| first_indexed | 2024-12-11T19:54:40Z |
| format | Article |
| id | doaj.art-69095867e67f4c95bef7238ab57b8380 |
| institution | Directory Open Access Journal |
| issn | 0917-5040 1349-9092 |
| language | English |
| last_indexed | 2024-12-11T19:54:40Z |
| publishDate | 2019-02-01 |
| publisher | Japan Epidemiological Association |
| record_format | Article |
| series | Journal of Epidemiology |
| spelling | doaj.art-69095867e67f4c95bef7238ab57b83802022-12-22T00:52:40ZengJapan Epidemiological AssociationJournal of Epidemiology0917-50401349-90922019-02-01292576010.2188/jea.JE20170180Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in JapanHitomi Fujita0Akihiro Hosono1Kiyoshi Shibata2Shoko Tsujimura3Kyoko Oka4Naoko Okamoto5Mayumi Kamiya6Fumi Kondo7Ryozo Wakabayashi8Mari Ichikawa9Tamaki Yamada10Sadao Suzuki11Department of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanOkazaki City Medical Association, Public Health Center, Aichi, JapanDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, JapanBackground: It is known that physical activity affects glucose metabolism. However, there have been no reports on the influence of physical activity earlier in life on subsequent glucose metabolism. Therefore, we analyzed the influence of physical activity in earlier decades of life on insulin resistance in middle aged and older residents in Japan. Methods: The subjects were 6,883 residents of Okazaki City between the ages of 40 and 79 years who underwent physical examinations at the Okazaki City Medical Association Public Health Center from April 2007 through August 2011. They gave informed consent for participation in the study. Data on individual characteristics were collected via a questionnaire and from the health examination records. Fasting blood glucose and insulin levels were used to calculate the homeostatic model assessment of insulin resistance (HOMA-IR). HOMA-IR >1.6 was considered to indicate insulin resistance for the purpose of logistic regression models. Results: The study sample included 3,683 men and 3,200 women for whom complete information was available. For those who exercised regularly throughout their teens to their 30s–40s, the odds ratio for having insulin resistance was 0.75 (95% confidence interval [CI], 0.58–0.96) for men and 0.76 (95% CI, 0.58–0.99) for women after adjusting for other variables, including age, body mass index, and present physical activity. A linear trend was also observed in both men and women. Conclusions: Subjects who have exercised regularly in the early decades of life are less likely to have insulin resistance later in life.https://www.jstage.jst.go.jp/article/jea/29/2/29_JE20170180/_pdfphysical activityinsulin resistanceHOMA-IRdiabetes mellituslifestyle related diseases |
| spellingShingle | Hitomi Fujita Akihiro Hosono Kiyoshi Shibata Shoko Tsujimura Kyoko Oka Naoko Okamoto Mayumi Kamiya Fumi Kondo Ryozo Wakabayashi Mari Ichikawa Tamaki Yamada Sadao Suzuki Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in Japan Journal of Epidemiology physical activity insulin resistance HOMA-IR diabetes mellitus lifestyle related diseases |
| title | Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in Japan |
| title_full | Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in Japan |
| title_fullStr | Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in Japan |
| title_full_unstemmed | Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in Japan |
| title_short | Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in Japan |
| title_sort | physical activity earlier in life is inversely associated with insulin resistance among adults in japan |
| topic | physical activity insulin resistance HOMA-IR diabetes mellitus lifestyle related diseases |
| url | https://www.jstage.jst.go.jp/article/jea/29/2/29_JE20170180/_pdf |
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