A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma
Advanced hepatocellular carcinoma carries a bad prognosis with a survival of only few months. Barcelona Clinic Liver Cancer (BCLC) Guidelines recommended sorafenib monotherapy as the treatment modality for advanced BCLC Stage C disease, citing a two-month increase in survival rates. Here, we highli...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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GESDAV
2018-03-01
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| Series: | Archives of Clinical and Experimental Surgery |
| Subjects: | |
| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=243853 |
| _version_ | 1828027162563706880 |
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| author | Zamri Zuhdi Azlanuddin Azman Affirul Chairil Ariffin Razman Jarmin Hairol Azrin Othman |
| author_facet | Zamri Zuhdi Azlanuddin Azman Affirul Chairil Ariffin Razman Jarmin Hairol Azrin Othman |
| author_sort | Zamri Zuhdi |
| collection | DOAJ |
| description | Advanced hepatocellular carcinoma carries a bad prognosis with a survival of only few months. Barcelona Clinic Liver Cancer (BCLC)
Guidelines recommended sorafenib monotherapy as the treatment modality for advanced BCLC Stage C disease, citing a two-month increase in survival rates. Here, we highlight a case with advanced HCC (BCLC Stage C) treated with combination therapy of liver resection and Sorafenib therapy. The patients current survival rate was beyond 10 months. We also discuss the current evidence on liver resection with Sorafenib therapy in hepatocellular carcinoma. The description of the case may benefit in future diagnosis and treatment. [Arch Clin Exp Surg 2018; 7(1.000): 29-32] |
| first_indexed | 2024-04-10T13:30:01Z |
| format | Article |
| id | doaj.art-69099c74c31b4a55ab0aab3854cfa47c |
| institution | Directory Open Access Journal |
| issn | 2146-8133 |
| language | English |
| last_indexed | 2024-04-10T13:30:01Z |
| publishDate | 2018-03-01 |
| publisher | GESDAV |
| record_format | Article |
| series | Archives of Clinical and Experimental Surgery |
| spelling | doaj.art-69099c74c31b4a55ab0aab3854cfa47c2023-02-15T16:11:39ZengGESDAVArchives of Clinical and Experimental Surgery2146-81332018-03-0171293210.5455/aces.20170503080643243853A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinomaZamri Zuhdi0Azlanuddin AzmanAffirul Chairil AriffinRazman JarminHairol Azrin OthmanDepartment of Surgery, Hepatobiliary Surgery Unit, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia Department of Surgery, Faculty of Medicine and Health Sciences, Islamic Science University of Malaysia, Negeri Sembilan, MalaysiaAdvanced hepatocellular carcinoma carries a bad prognosis with a survival of only few months. Barcelona Clinic Liver Cancer (BCLC) Guidelines recommended sorafenib monotherapy as the treatment modality for advanced BCLC Stage C disease, citing a two-month increase in survival rates. Here, we highlight a case with advanced HCC (BCLC Stage C) treated with combination therapy of liver resection and Sorafenib therapy. The patients current survival rate was beyond 10 months. We also discuss the current evidence on liver resection with Sorafenib therapy in hepatocellular carcinoma. The description of the case may benefit in future diagnosis and treatment. [Arch Clin Exp Surg 2018; 7(1.000): 29-32]http://www.ejmanager.com/fulltextpdf.php?mno=243853Hepatocellular carcinomasorafenibhepatectomy |
| spellingShingle | Zamri Zuhdi Azlanuddin Azman Affirul Chairil Ariffin Razman Jarmin Hairol Azrin Othman A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma Archives of Clinical and Experimental Surgery Hepatocellular carcinoma sorafenib hepatectomy |
| title | A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma |
| title_full | A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma |
| title_fullStr | A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma |
| title_full_unstemmed | A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma |
| title_short | A middle-aged man with a troubled liver: Combination therapy in advanced (BCLC Stage C) hepatocellular carcinoma |
| title_sort | middle aged man with a troubled liver combination therapy in advanced bclc stage c hepatocellular carcinoma |
| topic | Hepatocellular carcinoma sorafenib hepatectomy |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=243853 |
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