CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARÁ HOSPITAL INFANTIL
ABSTRACT Objective: To describe the clinical manifestations and severity of children and adolescents affected by COVID-19 treated at Sabará Hospital Infantil. Methods: This is a cross-sectional, retrospective, and observational study. All cases of COVID-19 confirmed by RT-qPCR of patients seen a...
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| Format: | Article |
| Language: | English |
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Sociedade de Pediatria de São Paulo
2020-11-01
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| Series: | Revista Paulista de Pediatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822021000100445&tlng=pt |
| _version_ | 1818339146962305024 |
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| author | Anna Clara Rabha Francisco Ivanildo de Oliveira Junior Thales Araújo de Oliveira Regina Grigolli Cesar Giuliana Fongaro Roberta Ferreira Mariano Clarice Neves Camargo Fátima Rodrigues Fernandes Gustavo Falbo Wandalsen |
| author_facet | Anna Clara Rabha Francisco Ivanildo de Oliveira Junior Thales Araújo de Oliveira Regina Grigolli Cesar Giuliana Fongaro Roberta Ferreira Mariano Clarice Neves Camargo Fátima Rodrigues Fernandes Gustavo Falbo Wandalsen |
| author_sort | Anna Clara Rabha |
| collection | DOAJ |
| description | ABSTRACT Objective: To describe the clinical manifestations and severity of children and adolescents affected by COVID-19 treated at Sabará Hospital Infantil. Methods: This is a cross-sectional, retrospective, and observational study. All cases of COVID-19 confirmed by RT-qPCR of patients seen at the hospital (emergency room, first-aid room, and ICU) were analyzed. The severity of the cases was classified according to the Chinese Consensus. Results: Among the 115 children included, a predominance of boys (57%) was verified, and the median age was two years. A total of 22 children were hospitalized, 12 in the ICU. Of the total, 26% had comorbidities with a predominance of asthma (13%). Fever, cough, and nasal discharge were the most frequent symptoms. Respiratory symptoms were reported by 58% of children and gastrointestinal symptoms, by 34%. Three children were asymptomatic, 81 (70%) had upper airway symptoms, 15 (13%) had mild pneumonia, and 16 (14%) had severe pneumonia. Hospitalized children were younger than non-hospitalized children (7 months vs. 36 months). In hospitalized patients, a higher frequency of irritability, dyspnea, drowsiness, respiratory distress, low oxygen saturation, and hepatomegaly was observed. Chest radiography was performed in 69 children with 45% of abnormal exams. No child required mechanical ventilation and there were no deaths. Conclusions: Most of children and adolescents affected by COVID-19 had mild upper airway symptoms. Clinical manifestations of COVID-19 were more severe among younger children who exhibited gastrointestinal and respiratory symptoms more frequently. |
| first_indexed | 2024-12-13T15:22:22Z |
| format | Article |
| id | doaj.art-690d7a42bb6c42a8b4752413d5503e05 |
| institution | Directory Open Access Journal |
| issn | 1984-0462 |
| language | English |
| last_indexed | 2024-12-13T15:22:22Z |
| publishDate | 2020-11-01 |
| publisher | Sociedade de Pediatria de São Paulo |
| record_format | Article |
| series | Revista Paulista de Pediatria |
| spelling | doaj.art-690d7a42bb6c42a8b4752413d5503e052022-12-21T23:40:32ZengSociedade de Pediatria de São PauloRevista Paulista de Pediatria1984-04622020-11-013910.1590/1984-0462/2021/39/2020305CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARÁ HOSPITAL INFANTILAnna Clara Rabhahttps://orcid.org/0000-0002-4336-1004Francisco Ivanildo de Oliveira Juniorhttps://orcid.org/0000-0003-0767-0536Thales Araújo de Oliveirahttps://orcid.org/0000-0003-4077-7933Regina Grigolli Cesarhttps://orcid.org/0000-0003-3776-9115Giuliana Fongarohttps://orcid.org/0000-0002-9556-2369Roberta Ferreira Marianohttps://orcid.org/0000-0001-5342-8738Clarice Neves Camargohttps://orcid.org/0000-0002-1710-459XFátima Rodrigues Fernandeshttps://orcid.org/0000-0002-4990-6466Gustavo Falbo Wandalsenhttps://orcid.org/0000-0003-2173-4380ABSTRACT Objective: To describe the clinical manifestations and severity of children and adolescents affected by COVID-19 treated at Sabará Hospital Infantil. Methods: This is a cross-sectional, retrospective, and observational study. All cases of COVID-19 confirmed by RT-qPCR of patients seen at the hospital (emergency room, first-aid room, and ICU) were analyzed. The severity of the cases was classified according to the Chinese Consensus. Results: Among the 115 children included, a predominance of boys (57%) was verified, and the median age was two years. A total of 22 children were hospitalized, 12 in the ICU. Of the total, 26% had comorbidities with a predominance of asthma (13%). Fever, cough, and nasal discharge were the most frequent symptoms. Respiratory symptoms were reported by 58% of children and gastrointestinal symptoms, by 34%. Three children were asymptomatic, 81 (70%) had upper airway symptoms, 15 (13%) had mild pneumonia, and 16 (14%) had severe pneumonia. Hospitalized children were younger than non-hospitalized children (7 months vs. 36 months). In hospitalized patients, a higher frequency of irritability, dyspnea, drowsiness, respiratory distress, low oxygen saturation, and hepatomegaly was observed. Chest radiography was performed in 69 children with 45% of abnormal exams. No child required mechanical ventilation and there were no deaths. Conclusions: Most of children and adolescents affected by COVID-19 had mild upper airway symptoms. Clinical manifestations of COVID-19 were more severe among younger children who exhibited gastrointestinal and respiratory symptoms more frequently.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822021000100445&tlng=ptCoronavirus infectionsChildPneumonia |
| spellingShingle | Anna Clara Rabha Francisco Ivanildo de Oliveira Junior Thales Araújo de Oliveira Regina Grigolli Cesar Giuliana Fongaro Roberta Ferreira Mariano Clarice Neves Camargo Fátima Rodrigues Fernandes Gustavo Falbo Wandalsen CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARÁ HOSPITAL INFANTIL Revista Paulista de Pediatria Coronavirus infections Child Pneumonia |
| title | CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARÁ HOSPITAL INFANTIL |
| title_full | CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARÁ HOSPITAL INFANTIL |
| title_fullStr | CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARÁ HOSPITAL INFANTIL |
| title_full_unstemmed | CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARÁ HOSPITAL INFANTIL |
| title_short | CLINICAL MANIFESTATIONS OF CHILDREN AND ADOLESCENTS WITH COVID-19: REPORT OF THE FIRST 115 CASES FROM SABARÁ HOSPITAL INFANTIL |
| title_sort | clinical manifestations of children and adolescents with covid 19 report of the first 115 cases from sabara hospital infantil |
| topic | Coronavirus infections Child Pneumonia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822021000100445&tlng=pt |
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