Combining Gene Transfer and Nonhuman Primates to Better Understand and Treat Parkinson’s Disease

Combining Gene Transfer and Nonhuman Primates to Better Understand and Treat Parkinson’s Disease

Parkinson’s disease (PD) is a progressive CNS disorder that is primarily associated with impaired movement. PD develops over decades and is linked to the gradual loss of dopamine delivery to the striatum, via the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). While t...

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Bibliographic Details
Main Authors: Christelle Lasbleiz, Nadine Mestre-Francés, Gina Devau, Maria-Rosario Luquin, Liliane Tenenbaum, Eric J. Kremer, Jean-Michel Verdier
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Parkinson’s disease
primate
CAV vectors
gene transfer
dopaminergic neurons
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00010/full

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