Hypoxia among patients on the liver-transplant waiting list

Background: Hepatopulmonary syndrome is formed by a triad of liver disease, intrapulmonary vascular dilatation and changes in blood gases. This condition is present in 4-32% of patients with cirrhosis. Aim : To analyze the blood gas changes data of patients in liver-transplant waiting list. Metho...

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Main Authors: Lucas Souto NACIF, Wellington ANDRAUS, Kathryn SARTORI, Carlos Marlon BENITES, Vinicius Rocha SANTOS, Joel Avancini ROCHA-FILHO, Luiz Carneiro D'ALBUQUERQUE
Format: Article
Language:English
Published: Colégio Brasileiro de Cirurgia Digestiva 2014-03-01
Series:ABCD: Arquivos Brasileiros de Cirurgia Digestiva
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202014000100056&tlng=en
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author Lucas Souto NACIF
Wellington ANDRAUS
Kathryn SARTORI
Carlos Marlon BENITES
Vinicius Rocha SANTOS
Joel Avancini ROCHA-FILHO
Luiz Carneiro D'ALBUQUERQUE
author_facet Lucas Souto NACIF
Wellington ANDRAUS
Kathryn SARTORI
Carlos Marlon BENITES
Vinicius Rocha SANTOS
Joel Avancini ROCHA-FILHO
Luiz Carneiro D'ALBUQUERQUE
author_sort Lucas Souto NACIF
collection DOAJ
description Background: Hepatopulmonary syndrome is formed by a triad of liver disease, intrapulmonary vascular dilatation and changes in blood gases. This condition is present in 4-32% of patients with cirrhosis. Aim : To analyze the blood gas changes data of patients in liver-transplant waiting list. Method: Clinical data of 279 patients in liver transplantation waiting list in May 2013 were studied. Overall patient was analyzed by the demographic aspects, laboratorial and image findings on exams that determine lung disease (hypoxemia) in these cirrhotic patients. The mean values and standard deviations were used to examine normally distributed variables. Results: There was a high prevalence of male patients (68%); the mean age was 51(±5,89) years, and the predominant reason for listing was hepatitis C cirrhosis. The MELD score mean was 16±5,89, without prioritization or special situation. The most common blood type was O in 129 cases (46%) and the mean of body max index was 25,94±4,58. Regarding arterial blood gas tests was observed 214 patients with PaO2 <90 mmHg, 80 with PaO2 <80 mmHg and 39 with PaO2 <50 mmHg. In relation to O2 saturation, 50 patients had <90%, 33 <80% and 10 <50%. Conclusion: Was observed a high rate of hypoxemia in patients on waiting list liver transplant. Due to the high severity and morbidity, is suggested better monitoring and therapeutic support to hypoxemic patients on liver transplant waiting list.
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spelling doaj.art-690dcca6ed5e4cb48e50b1cf8f74d4552022-12-21T19:47:25ZengColégio Brasileiro de Cirurgia DigestivaABCD: Arquivos Brasileiros de Cirurgia Digestiva0102-67202014-03-01271565810.1590/s0102-67202014000100014Hypoxia among patients on the liver-transplant waiting listLucas Souto NACIFWellington ANDRAUSKathryn SARTORICarlos Marlon BENITESVinicius Rocha SANTOSJoel Avancini ROCHA-FILHOLuiz Carneiro D'ALBUQUERQUEBackground: Hepatopulmonary syndrome is formed by a triad of liver disease, intrapulmonary vascular dilatation and changes in blood gases. This condition is present in 4-32% of patients with cirrhosis. Aim : To analyze the blood gas changes data of patients in liver-transplant waiting list. Method: Clinical data of 279 patients in liver transplantation waiting list in May 2013 were studied. Overall patient was analyzed by the demographic aspects, laboratorial and image findings on exams that determine lung disease (hypoxemia) in these cirrhotic patients. The mean values and standard deviations were used to examine normally distributed variables. Results: There was a high prevalence of male patients (68%); the mean age was 51(±5,89) years, and the predominant reason for listing was hepatitis C cirrhosis. The MELD score mean was 16±5,89, without prioritization or special situation. The most common blood type was O in 129 cases (46%) and the mean of body max index was 25,94±4,58. Regarding arterial blood gas tests was observed 214 patients with PaO2 <90 mmHg, 80 with PaO2 <80 mmHg and 39 with PaO2 <50 mmHg. In relation to O2 saturation, 50 patients had <90%, 33 <80% and 10 <50%. Conclusion: Was observed a high rate of hypoxemia in patients on waiting list liver transplant. Due to the high severity and morbidity, is suggested better monitoring and therapeutic support to hypoxemic patients on liver transplant waiting list.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202014000100056&tlng=enLiver transplantationHypoxemiaLiver-transplant waiting listHepatopulmonary syndrome
spellingShingle Lucas Souto NACIF
Wellington ANDRAUS
Kathryn SARTORI
Carlos Marlon BENITES
Vinicius Rocha SANTOS
Joel Avancini ROCHA-FILHO
Luiz Carneiro D'ALBUQUERQUE
Hypoxia among patients on the liver-transplant waiting list
ABCD: Arquivos Brasileiros de Cirurgia Digestiva
Liver transplantation
Hypoxemia
Liver-transplant waiting list
Hepatopulmonary syndrome
title Hypoxia among patients on the liver-transplant waiting list
title_full Hypoxia among patients on the liver-transplant waiting list
title_fullStr Hypoxia among patients on the liver-transplant waiting list
title_full_unstemmed Hypoxia among patients on the liver-transplant waiting list
title_short Hypoxia among patients on the liver-transplant waiting list
title_sort hypoxia among patients on the liver transplant waiting list
topic Liver transplantation
Hypoxemia
Liver-transplant waiting list
Hepatopulmonary syndrome
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202014000100056&tlng=en
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