Real-time identification of epistatic interactions in SARS-CoV-2 from large genome collections

Abstract Background The emergence of the SARS-CoV-2 virus has highlighted the importance of genomic epidemiology in understanding the evolution of pathogens and guiding public health interventions. The Omicron variant in particular has underscored the role of epistasis in the evolution of lineages w...

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Bibliographic Details
Main Authors: Gabriel Innocenti, Maureen Obara, Bibiana Costa, Henning Jacobsen, Maeva Katzmarzyk, Luka Cicin-Sain, Ulrich Kalinke, Marco Galardini
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-024-03355-y