Dysregulated Notch Signaling in the Airway Epithelium of Children with Wheeze

Dysregulated Notch Signaling in the Airway Epithelium of Children with Wheeze

The airway epithelium of children with wheeze is characterized by defective repair that contributes to disease pathobiology. Dysregulation of developmental processes controlled by Notch has been identified in chronic asthma. However, its role in airway epithelial cells of young children with wheeze,...

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Bibliographic Details
Main Authors: Thomas Iosifidis, Erika N. Sutanto, Samuel T. Montgomery, Patricia Agudelo-Romero, Kevin Looi, Kak-Ming Ling, Nicole C. Shaw, Luke W. Garratt, Jessica Hillas, Kelly M. Martinovich, Elizabeth Kicic-Starcevich, Shyan Vijayasekaran, Francis J. Lannigan, Paul J. Rigby, Darryl A. Knight, Stephen M. Stick, Anthony Kicic
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Journal of Personalized Medicine
Subjects:
pediatrics
wheeze
airway epithelium
wound repair
Notch
Online Access:https://www.mdpi.com/2075-4426/11/12/1323

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