Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD

Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD

Xanthine oxidase (XO) contributes to oxidative stress and vascular disease. Hyperuricemia and gout are common in patients with chronic kidney disease (CKD), a population at increased risk of vascular disease. We evaluated effects of allopurinol on serum XO activity and metabolome of CKD patients who...

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Bibliographic Details
Main Authors: Mingyao Sun, Nicole Hines, Diego Scerbo, Jane Buchanan, Chaorong Wu, Patrick Ten Eyck, Diana Zepeda-Orozco, Eric B. Taylor, Diana I. Jalal
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antioxidants
Subjects:
xanthine oxidase
urate
chronic kidney disease
Online Access:https://www.mdpi.com/2076-3921/11/7/1297

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