Comparative evaluation of Comfilcon A and Senofilcon A bandage contact lenses after transepithelial photorefractive keratectomy
Purpose: To evaluate and compare Comfilcon A and Senofilcon A silicone hydrogel contact lenses used as a therapeutic bandage following transepithelial excimer laser photorefractive keratectomy (PRK). Methods: Patients undergoing transepithelial PRK for myopia were prospectively recruited. Included p...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-01-01
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| Series: | Journal of Optometry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1888429614000077 |
| _version_ | 1818872968513585152 |
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| author | Achyut Mukherjee Antonis Ioannides Ioannis Aslanides |
| author_facet | Achyut Mukherjee Antonis Ioannides Ioannis Aslanides |
| author_sort | Achyut Mukherjee |
| collection | DOAJ |
| description | Purpose: To evaluate and compare Comfilcon A and Senofilcon A silicone hydrogel contact lenses used as a therapeutic bandage following transepithelial excimer laser photorefractive keratectomy (PRK).
Methods: Patients undergoing transepithelial PRK for myopia were prospectively recruited. Included patients had a Comfilcon A silicone hydrogel lens inserted in one eye, with a Senofilcon A lens in the contralateral eye. Postoperative assessment of subjective pain, epithelial healing and visual recovery was at day 1, 3 and 7. Contact lens factors including centration, movement and deposits were assessed.
Results: 48 eyes of 24 patients were included in the study. Mean age was 31 years (SD 11) and mean refractive error −4.5 D (SD 1.8). Mean pain score at day 1 was significantly higher in the Comfilcon group at 4.6 (SD 2.7) vs. 1.5 (SD2.5) in the Senofilcon group (P < 0.005). Mean time to healing was 3.17 days (SD 0.37) in the Comfilcon group, and 3.21 days (SD 0.4) in the Senofilcon group, with no difference in defect size. There was a pronounced central raphe in 1 eye in the Comfilcon group vs. 5 eyes in the Senofilcon group (P = 0.19). Significantly more eyes demonstrated no lens movement in the Senofilcon group (18 vs. 4, P = 0.0001).
Conclusion: The variation in material characteristics and lens geometry of different silicone hydrogel lenses affects their clinical characteristics in therapeutic roles. Other factors than oxygen permeability may affect pain and epithelial healing, with superior pain relief from the less permeable Senofilcon lens in this study. |
| first_indexed | 2024-12-19T12:47:14Z |
| format | Article |
| id | doaj.art-6922a0201fa24effac24cb82ef39c4d7 |
| institution | Directory Open Access Journal |
| issn | 1888-4296 |
| language | English |
| last_indexed | 2024-12-19T12:47:14Z |
| publishDate | 2015-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Optometry |
| spelling | doaj.art-6922a0201fa24effac24cb82ef39c4d72022-12-21T20:20:43ZengElsevierJournal of Optometry1888-42962015-01-0181273210.1016/j.optom.2014.02.002Comparative evaluation of Comfilcon A and Senofilcon A bandage contact lenses after transepithelial photorefractive keratectomyAchyut MukherjeeAntonis IoannidesIoannis AslanidesPurpose: To evaluate and compare Comfilcon A and Senofilcon A silicone hydrogel contact lenses used as a therapeutic bandage following transepithelial excimer laser photorefractive keratectomy (PRK). Methods: Patients undergoing transepithelial PRK for myopia were prospectively recruited. Included patients had a Comfilcon A silicone hydrogel lens inserted in one eye, with a Senofilcon A lens in the contralateral eye. Postoperative assessment of subjective pain, epithelial healing and visual recovery was at day 1, 3 and 7. Contact lens factors including centration, movement and deposits were assessed. Results: 48 eyes of 24 patients were included in the study. Mean age was 31 years (SD 11) and mean refractive error −4.5 D (SD 1.8). Mean pain score at day 1 was significantly higher in the Comfilcon group at 4.6 (SD 2.7) vs. 1.5 (SD2.5) in the Senofilcon group (P < 0.005). Mean time to healing was 3.17 days (SD 0.37) in the Comfilcon group, and 3.21 days (SD 0.4) in the Senofilcon group, with no difference in defect size. There was a pronounced central raphe in 1 eye in the Comfilcon group vs. 5 eyes in the Senofilcon group (P = 0.19). Significantly more eyes demonstrated no lens movement in the Senofilcon group (18 vs. 4, P = 0.0001). Conclusion: The variation in material characteristics and lens geometry of different silicone hydrogel lenses affects their clinical characteristics in therapeutic roles. Other factors than oxygen permeability may affect pain and epithelial healing, with superior pain relief from the less permeable Senofilcon lens in this study.http://www.sciencedirect.com/science/article/pii/S1888429614000077Photorefractive keratectomyTransepithelial PRKSilicone hydrogel contact lensBandage contact lens |
| spellingShingle | Achyut Mukherjee Antonis Ioannides Ioannis Aslanides Comparative evaluation of Comfilcon A and Senofilcon A bandage contact lenses after transepithelial photorefractive keratectomy Journal of Optometry Photorefractive keratectomy Transepithelial PRK Silicone hydrogel contact lens Bandage contact lens |
| title | Comparative evaluation of Comfilcon A and Senofilcon A bandage contact lenses after transepithelial photorefractive keratectomy |
| title_full | Comparative evaluation of Comfilcon A and Senofilcon A bandage contact lenses after transepithelial photorefractive keratectomy |
| title_fullStr | Comparative evaluation of Comfilcon A and Senofilcon A bandage contact lenses after transepithelial photorefractive keratectomy |
| title_full_unstemmed | Comparative evaluation of Comfilcon A and Senofilcon A bandage contact lenses after transepithelial photorefractive keratectomy |
| title_short | Comparative evaluation of Comfilcon A and Senofilcon A bandage contact lenses after transepithelial photorefractive keratectomy |
| title_sort | comparative evaluation of comfilcon a and senofilcon a bandage contact lenses after transepithelial photorefractive keratectomy |
| topic | Photorefractive keratectomy Transepithelial PRK Silicone hydrogel contact lens Bandage contact lens |
| url | http://www.sciencedirect.com/science/article/pii/S1888429614000077 |
| work_keys_str_mv | AT achyutmukherjee comparativeevaluationofcomfilconaandsenofilconabandagecontactlensesaftertransepithelialphotorefractivekeratectomy AT antonisioannides comparativeevaluationofcomfilconaandsenofilconabandagecontactlensesaftertransepithelialphotorefractivekeratectomy AT ioannisaslanides comparativeevaluationofcomfilconaandsenofilconabandagecontactlensesaftertransepithelialphotorefractivekeratectomy |